DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP5A and Arhgap30

DIOPT Version :9

Sequence 1:	NP_727007.1	Gene:	RhoGAP5A / 31473	FlyBaseID:	FBgn0029778	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001102547.1	Gene:	Arhgap30 / 498282	RGDID:	1561419	Length:	1104	Species:	Rattus norvegicus

Alignment Length:	203	Identity:	60/203 - (29%)
Similarity:	104/203 - (51%)	Gaps:	16/203 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   301 VFGTDLTTMVQLEPHHQIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDREGEKTDM 365
            |||.||...:| :...::|.|:|.|.|.|:..|:: :||||:||.:..|:.|:...:.| .|.|:
  Rat    17 VFGCDLREHLQ-QSGQEVPQVLRSCAEFVQEYGVV-DGIYRLSGVSSNIQKLRQEFEAE-RKPDL 78

  Fly   366 SETAY-GNVNVIAGTLKLYLRLLPVPLITFQAYPSFMAAGRTGKQAEQRQLMAEAVRRLPPAHHS 429
            ....| .:::.::...|.|.|.||.||:|::.|..|..|.....:.|:...:.|.::.||..::.
  Rat    79 RRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVAVQLEPERLVKILEVLQELPVPNYR 143

  Fly   430 CLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLI-----------ATPQHMTNLTEEIFMLSSL 483
            .|::::.||..:||..|...|:..|||.|:||.|:           .|...|....:.| ::..:
  Rat   144 TLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSI-VVEFI 207

  Fly   484 ITHCKTIF 491
            :||...:|
  Rat   208 LTHVDQLF 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215
		C1_1	242..294	CDD:278556
		RhoGAP_chimaerin	302..491	CDD:239837	58/200 (29%)
Arhgap30	NP_001102547.1	RhoGAP_CdGAP	16..210	CDD:239849	57/196 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1300981at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010