Protein Alignment RhoGAP5A and RhoGAP100F

DIOPT Version :10

• Sequence 1: NP_727007.1
• Gene: RhoGAP5A / 31473
• FlyBaseID: FBgn0029778
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001163786.1
• Gene: RhoGAP100F / 43758
• FlyBaseID: FBgn0039883
• Length: 1866
• Species: Drosophila melanogaster
• Alignment Length: 521
• Identity: 130/521 - (24%)
• Similarity: 195/521 - (37%)
• Gaps: 145/521 - (27%)

  Fly     3 RNTEA---------GAG--NANTG-------------GSGGVGGAPEPSSPVQKVWKPELYKLQL 43
            ||||:         |.|  :.|.|             .|..:|||....||..:..: :|.:|..
  Fly   682 RNTESIYSSRNHILGTGTLDRNMGLTRPISALPVRSMSSQHIGGAGSIRSPSIRRMR-QLLELSA 745

  Fly    44 ---------------EAPAPCPLRCQRTLPLP-------PA-----KSTAEAVEANNLAGRLYGS 81
                           ::|||.|   ..|||.|       ||     |.....|:...::|.|:
  Fly   746 GPASPSGSILSTGGHQSPAPTP---SATLPRPHRQIDINPAEFAKYKLDKPIVDIGGISGMLW-- 805

  Fly    82 EYHGLMGHLEAEQLLANARDGSYFVRRSPQSDGYYTLSLRFNKRPKHYKLLYKPGVGHYLRGQDK 146
                  .||.|.:.|..|.:|:.......|:...|.: :..::..|...:         :|..|.
  Fly   806 ------IHLLAGRGLRTAPEGAAGTATQGQTRDLYCV-IECDRVHKARTV---------VRSGDL 854

  Fly   147 RFDTVHDMVADGLINFHMQLHASPIIQQINQQTKNCYQQSPYMTLNGRKLRALSNELGKAAAKES 211
            :||.......|.:.|  .||...........:.|.||          |...:||:.|
  Fly   855 QFDWDESFELDLVGN--KQLDVLVYSWDPQHRHKLCY----------RGAISLSSIL-------- 899

  Fly   212 KESPAEEKEQKQEEPPPPAVDPMPLVYEKPHHFKVHTFKGLNWCEFCANFLWGFTAQGVKCEACG 276
            ::||..:...|        |:|...:|.:..|               .:.|..:..:|:.....|
  Fly   900 RQSPLHQLALK--------VEPRGTIYIRMRH---------------TDPLALYKRRGLPSLRAG 941

  Fly   277 FVAHSKCSELVPPKCVPDLKRIRGVFGTDLTTMVQLEPHH-----QIPFVVRRCVEEVEARGMLQ 336
            :               |.|      ||.||.|:|..|..:     .:|.|:||||||||.||:..
  Fly   942 Y---------------PTL------FGADLETVVNRESKNAPGSAPVPIVLRRCVEEVERRGLDI 985

  Fly   337 EGIYRVSGFADEIEALKLALDREGEKTDMSETAYGNVNVIAGTLKLYLRLLPVPLIT---FQAYP 398
            .|:||:.|.|.:...|:.|.:|.....:::.....::|||.|.||.|||.||.||.|   ||...
  Fly   986 IGLYRLCGSATKKRLLREAFERNSRAVELTPEHVPDINVITGVLKDYLRELPEPLFTRCLFQMTV 1050

  Fly   399 SFMAAGRTGKQAEQRQLMAEAVRRLPPAHHSCLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTL 463
            ..:|...........:||...:..||.|:.:.|.::|:||..|.|:...|||:...||||..|.|
  Fly  1051 DALAVCLPDDPEGNAKLMLSILDCLPRANRATLVFLLDHLSLVVSNSERNKMSAQALATVMGPPL 1115

  Fly   464 I 464
            :
  Fly  1116 M 1116

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215	17/90 (19%)
		C1_CHN	241..293	CDD:410356	4/51 (8%)
		RhoGAP_chimaerin	302..491	CDD:239837	64/171 (37%)
RhoGAP100F	NP_001163786.1	PDZ_Par6-like	178..261	CDD:467202
		C2	804..905	CDD:175973	27/138 (20%)
		RhoGAP_SYD1	946..1144	CDD:239844	64/171 (37%)
		DUF5585	1349..>1604	CDD:465521