Protein Alignment RhoGAP5A and PKD

DIOPT Version :10

• Sequence 1: NP_727007.1
• Gene: RhoGAP5A / 31473
• FlyBaseID: FBgn0029778
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001262705.1
• Gene: PKD / 42203
• FlyBaseID: FBgn0038603
• Length: 906
• Species: Drosophila melanogaster
• Alignment Length: 318
• Identity: 67/318 - (21%)
• Similarity: 115/318 - (36%)
• Gaps: 122/318 - (38%)

  Fly   235 PLVYE-------KPHHFKVHTFKGLNWCEFCANFLWGFTAQGVKCEACGFVAHSKCSELVPPKCV 292
            |::|.       |||...||::||..:|:||...|:|...||:||:.||...|.:|...:|..|.
  Fly    91 PILYPTSEMPTLKPHSLNVHSYKGPTFCDFCGEMLFGLVRQGLKCDGCGQNYHKRCVVKIPNNCN 155

  Fly   293 PD----------LKRIRGVFGTDLTTMVQLE---------------------------------- 313
            ..          |:..|...|:...::|..|
  Fly   156 RSNDATSRRSFTLQAPRSPSGSSQQSLVSTEDSTGRNDSSSSLNIPGRHQRTHSSGSRNGLMVLR 220

  Fly   314 -PH------HQIPFVVRRCVEEVEARGMLQEGI------------------YRVSGFADEIEALK 353
             ||      :.||.|.:.|.:.:  :|:.::|:                  :..:|.| ::..|:
  Fly   221 IPHTFMVHTYGIPTVCQLCKKLL--KGLFKQGLQCRDCQYNTHKKCMDKVPHDCTGEA-QLSQLQ 282

  Fly   354 L---ALDREG---EKTDMSE----TAYG--------NVNVIAGTLKLYLRLLPVPLITFQAYP-- 398
            :   |.:|:.   |:.|.|:    :.||        .||::||.    .|..|..|......|
  Fly   283 IQAGAKERDNFFREEFDDSDGDDGSEYGKYKSAMSSGVNLVAGR----PREAPKALTNAHNSPPE 343

  Fly   399 ---------SFMAAGRTGK-----QAEQRQLMAEAVRRLPPAHHSCLQYM--LEHLKR 440
                     |.::.|.|.|     |:||.|   .:....|.|:...::.:  ::|.|:
  Fly   344 LVNGGLVDDSSVSGGETSKSSSDGQSEQSQ---SSTSSSPSANIPLMRIVQSVKHTKK 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215
		C1_CHN	241..293	CDD:410356	21/51 (41%)
		RhoGAP_chimaerin	302..491	CDD:239837	41/234 (18%)
PKD	NP_001262705.1	C1_PKD_rpt1	102..157	CDD:410345	22/54 (41%)
		C1_PKD_rpt2	222..275	CDD:410346	8/54 (15%)
		PH_PKD	396..522	CDD:269945	1/3 (33%)
		STKc_PKD	539..798	CDD:270984