DRSC/TRiP Functional Genomics Resources

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Protein Alignment RhoGAP5A and Arhgap1

DIOPT Version :10

Sequence 1:NP_727007.1 Gene:RhoGAP5A / 31473 FlyBaseID:FBgn0029778 Length:494 Species:Drosophila melanogaster
Sequence 2:NP_001101217.2 Gene:Arhgap1 / 311193 RGDID:1306068 Length:439 Species:Rattus norvegicus


Alignment Length:221 Identity:62/221 - (28%)
Similarity:105/221 - (47%) Gaps:19/221 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   257 FCANFLWGFTAQGVKCEACG----------FVAHSKCSELVPPKCVPDLKRI-RGVFGTDLTTMV 310
            |..|:| ...::.||.|..|          |:..::.|....||.:|....: ...||..|..:.
  Rat   187 FYVNYL-SELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLR 250

  Fly   311 QLEPHHQ-IPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDREGEKTDMSETAYGNVN 374
            :..|:.: ||.|:|..|..::|..:..|||:|.|.....:..::...:. |...|..:  |..::
  Rat   251 EKNPNQEPIPIVLRETVAYLQAHALTAEGIFRRSANTQVVREVQQKYNM-GLPVDFDQ--YNELH 312

  Fly   375 VIAGTLKLYLRLLPVPLITFQAYPSFMAAGRTGKQAEQR-QLMAEAVRRLPPAHHSCLQYMLEHL 438
            :.|..||.:||.||.||:||..||..:  |......:|| ::..:.::.||..::..|.::...|
  Rat   313 LPAVILKTFLRELPEPLLTFDLYPHIV--GFLDLDDDQRVEVTQQVLQTLPEENYRVLHFLTAFL 375

  Fly   439 KRVASHYAVNKMNEHNLATVFAPTLI 464
            .:|::|...|:||..|||.||.|.|:
  Rat   376 VQVSAHSYQNRMNNTNLAVVFGPNLL 401

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhoGAP5ANP_727007.1 SH2_a2chimerin_b2chimerin 75..166 CDD:198215
C1_CHN 241..293 CDD:410356 11/45 (24%)
RhoGAP_chimaerin 302..491 CDD:239837 50/165 (30%)
Arhgap1NP_001101217.2 CRAL_TRIO_2 82..216 CDD:463965 7/29 (24%)
RhoGAP-p50rhoGAP 239..431 CDD:239869 50/168 (30%)
Blue background indicates that the domain is not in the aligned region.

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