Protein Alignment RhoGAP5A and Arhgap23

DIOPT Version :10

• Sequence 1: NP_727007.1
• Gene: RhoGAP5A / 31473
• FlyBaseID: FBgn0029778
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_063126213.1
• Gene: Arhgap23 / 303501
• RGDID: 1309742
• Length: 1506
• Species: Rattus norvegicus
• Alignment Length: 333
• Identity: 83/333 - (24%)
• Similarity: 134/333 - (40%)
• Gaps: 67/333 - (20%)

  Fly   171 IIQQINQQTKNCYQQSPYMTLN---GRKLRALSNELGKAAA---KESKESPAEEKEQKQEEPPPP 229
            |.:::|...|..:...|....:   .|.|..|.:|..|..|   ..:::.||..||.....|..|
  Rat   849 ISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQTAVRGLRTQDQPAGSKEDSVTTPKTP 913

  Fly   230 AVDPMPLVYEKPHHFKVHTFKGLNWCEFCANFLWGFTAQGVKCEACGFVAHSKCSELVPPKCVPD 294
                                             ||.          ..:..:|       |..|
  Rat   914 ---------------------------------WGI----------NIIKKNK-------KAAP- 927

  Fly   295 LKRIRGVFGTDLTTMVQLEPHHQIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDRE 359
                 ..||..|........:.::|.:|..|...|||||:...|||||.|....:.:|:..|:|.
  Rat   928 -----RAFGIRLEDCQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG 987

  Fly   360 GEKTDMSETAYGNVNVIAGTLKLYLRLLPVPLITFQAYPSFMAAGRTGKQAEQRQLMAEAVRRLP 424
            ....::.:..:.::|||:..||.:.|.||.||.|...|..|:.|.|.....|:.:.:.:.:|.||
  Rat   988 PSDINLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDLP 1052

  Fly   425 PAHHSCLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLIATPQH-----MTNLTEEIFMLSSLI 484
            ..::..|::::.|||.:|.|...|||...|||.||.|||:.|.:.     :|::.:...::.:||
  Rat  1053 GHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLI 1117

  Fly   485 THCKTIFA 492
            .|....|:
  Rat  1118 QHSDWFFS 1125

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215
		C1_CHN	241..293	CDD:410356	4/51 (8%)
		RhoGAP_chimaerin	302..491	CDD:239837	61/193 (32%)
Arhgap23	XP_063126213.1	None