Protein Alignment RhoGAP5A and Arhgap15

DIOPT Version :9

• Sequence 1: NP_727007.1
• Gene: RhoGAP5A / 31473
• FlyBaseID: FBgn0029778
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001013939.1
• Gene: Arhgap15 / 295635
• RGDID: 1359304
• Length: 482
• Species: Rattus norvegicus
• Alignment Length: 443
• Identity: 108/443 - (24%)
• Similarity: 181/443 - (40%)
• Gaps: 90/443 - (20%)

  Fly    90 LEAEQLLANAR--DGSYFVRRSPQSDGYYTLS---LRFNKRPKHYKLLYKPGV------------ 137
            :|.|..|..|:  ||...:|:: .|..:..||   |.|.|.||...|   |.|
  Rat    88 VEKEGYLQKAKIADGGKKLRKN-WSTSWIVLSGRKLEFYKDPKQQAL---PNVKPRPNAESVDLC 148

  Fly   138 GHYLR--GQDKRF-DTVHDMVADGLINFHMQLHASPIIQQINQQTKNCYQQSPYMTLNGRKLRAL 199
            |.::.  .:||.. .:|..:.......|.:|.....:|.......||...:.|.....|
  Rat   149 GAHIEWAAKDKSSKKSVFQITTASGNEFLLQSDIDFLILDWFHAIKNAIDRLPKNPSFG------ 207

  Fly   200 SNELGKAAAKESKESPA----EEKEQKQEEPPPPAVDPMPLVYEKPHHFKVHTFKGLNWCEFCAN 260
            |.||.......|.|.|:    :.||||.|.             .|...|::|
  Rat   208 SLELFSFQRSSSSEQPSHCHIDRKEQKPEN-------------RKSFMFRLH------------- 246

  Fly   261 FLWGFTAQGVKCEACGFVAHSKCSELVPPKCVPDLKRIR-------GVFGTDLTTMVQLEPHHQI 318
                   ..|...:......|:..:.:..:  |.||.::       .:||:.|.|:.:.| |..:
  Rat   247 -------HSVSDTSDKNRVKSRLKKFISRR--PSLKTLQEKGIIKDQIFGSHLHTVCERE-HSTV 301

  Fly   319 PFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDREGEKTDMSETAYGNVNVIAGTLKLY 383
            |:.|::|:|.||.||:..:|||||||....|:.|:..:::| ||.::.::.:.:::|:.|.||::
  Rat   302 PWFVKQCIEAVEKRGLEVDGIYRVSGNLATIQKLRFIVNQE-EKLNLDDSQWEDIHVVTGALKMF 365

  Fly   384 LRLLPVPLITFQAYPSFMAAGRTGKQAEQRQLMAEAVRRLPPAHHSCLQYMLEHLKRVASHYAVN 448
            .|.|..||..:..:..|:.|.:......:.:.|...|:.|||.:|..::.:..||.::.:..|.|
  Rat   366 FRELSEPLFPYSFFERFVEAIKKQDSDAKIETMKSLVKSLPPPNHDTMKILFGHLTKIVAKAAQN 430

  Fly   449 KMNEHNLATVFAPTLIATPQHMTNLTEEI--------FMLSSLITHCKTIFAT 493
            .|:..:|..||.|||:.......|:...:        |||    |....||::
  Rat   431 LMSTQSLGIVFGPTLLRAENESGNVAVHMVYQNQVAEFML----TEYDKIFSS 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215	23/95 (24%)
		C1_1	242..294	CDD:278556	4/51 (8%)
		RhoGAP_chimaerin	302..491	CDD:239837	58/196 (30%)
Arhgap15	NP_001013939.1	PH	88..197	CDD:278594	27/112 (24%)
		PH_ARHGAP9-like	89..199	CDD:270053	27/113 (24%)
		RhoGAP_ARHGAP27_15_12_9	286..472	CDD:239868	57/191 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1300981at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920