DRSC/TRiP Functional Genomics Resources

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Protein Alignment RhoGAP5A and Arhgap1

DIOPT Version :10

Sequence 1:NP_727007.1 Gene:RhoGAP5A / 31473 FlyBaseID:FBgn0029778 Length:494 Species:Drosophila melanogaster
Sequence 2:NP_001139374.1 Gene:Arhgap1 / 228359 MGIID:2445003 Length:479 Species:Mus musculus


Alignment Length:221 Identity:61/221 - (27%)
Similarity:100/221 - (45%) Gaps:19/221 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   257 FCANFLWGFTAQGVKCEACG----------FVAHSKCSELVPPKCVPDLKRI-RGVFGTDLTTMV 310
            |..|:| ...::.||.|..|          |:..::.|....||.:|....: ...||..|..:.
Mouse   227 FYVNYL-SELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLQ 290

  Fly   311 QLEP-HHQIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDREGEKTDMSETAYGNVN 374
            :..| ...||.|:|..|..::|..:..|||:|.|.....:..::...:. |...|..:  |..::
Mouse   291 EKSPGQDPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNM-GLPVDFDQ--YNELH 352

  Fly   375 VIAGTLKLYLRLLPVPLITFQAYPSFMAAGRTGKQAEQR-QLMAEAVRRLPPAHHSCLQYMLEHL 438
            :.|..||.:||.||.||:||..||.  ..|.......|| ::..:.::.||..::..|.::...|
Mouse   353 LPAVILKTFLRELPEPLLTFDLYPH--VVGFLNIDESQRVEVTQQVLQTLPEENYQVLHFLTAFL 415

  Fly   439 KRVASHYAVNKMNEHNLATVFAPTLI 464
            .::::|...|||...|||.||.|.|:
Mouse   416 VQISAHCDQNKMTNTNLAVVFGPNLL 441

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhoGAP5ANP_727007.1 SH2_a2chimerin_b2chimerin 75..166 CDD:198215
C1_CHN 241..293 CDD:410356 11/45 (24%)
RhoGAP_chimaerin 302..491 CDD:239837 49/165 (30%)
Arhgap1NP_001139374.1 CRAL_TRIO_2 122..256 CDD:463965 7/29 (24%)
RhoGAP-p50rhoGAP 279..471 CDD:239869 49/168 (29%)
Blue background indicates that the domain is not in the aligned region.

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