DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP5A and arhgap30

DIOPT Version :9

Sequence 1:	NP_727007.1	Gene:	RhoGAP5A / 31473	FlyBaseID:	FBgn0029778	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_031747713.1	Gene:	arhgap30 / 100496292	XenbaseID:	XB-GENE-5915753	Length:	1431	Species:	Xenopus tropicalis

Alignment Length:	204	Identity:	64/204 - (31%)
Similarity:	107/204 - (52%)	Gaps:	20/204 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   302 FGTDLTTMVQLEPHHQIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDREGEKTDMS 366
            ||.||...:.:. ..::|.|:|.|.:.||..|:: :||||:.|.|..:..|:...|.| .:.|:|
Frog    21 FGCDLLEHLSIS-GLEVPQVLRSCTDFVEEHGVV-DGIYRLCGIASNVHKLRQEFDME-RQPDLS 82

  Fly   367 ETAY-GNVNVIAGTLKLYLRLLPVPLITFQAYPSFMAAGRTGKQAEQRQL--MAEAVRRLPPAHH 428
            :..| .:|:.::...|.|.|.||.||:|:|.|..|  |.....|.|:::|  :.|.::.||..|:
Frog    83 KDTYLQDVHCVSSLCKAYFRELPNPLLTYQLYDKF--ADAVAIQLEEQRLIKIKEVLKELPLPHY 145

  Fly   429 SCLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLI-----------ATPQHMTNLTEEIFMLSS 482
            ..|:|::.||.|:||..:...|:..|||.|:||.|:           .|...|....:.| ::..
Frog   146 RTLEYLMRHLLRMASFSSQTNMHARNLAIVWAPNLLRSKDIESSGFNGTAAFMEVRIQSI-VVEF 209

  Fly   483 LITHCKTIF 491
            ::||.:.:|
Frog   210 ILTHVEQLF 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215
		C1_1	242..294	CDD:278556
		RhoGAP_chimaerin	302..491	CDD:239837	63/202 (31%)
arhgap30	XP_031747713.1	RhoGAP_CdGAP	19..213	CDD:239849	61/197 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1300981at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010