Protein Alignment RhoGAP5A and syde2

DIOPT Version :9

• Sequence 1: NP_727007.1
• Gene: RhoGAP5A / 31473
• FlyBaseID: FBgn0029778
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_002931720.3
• Gene: syde2 / 100494956
• XenbaseID: XB-GENE-980337
• Length: 1547
• Species: Xenopus tropicalis
• Alignment Length: 614
• Identity: 136/614 - (22%)
• Similarity: 206/614 - (33%)
• Gaps: 198/614 - (32%)

  Fly     2 PRNTEAGAGNAN-------TGGSGGVGGAPEPSSPVQKV-WK---------------------PE 37
            |::.|:|||..:       |........:|.||.....: |.                     ||
 Frog   839 PKSNESGAGVQSPIKPISPTATEFSPPSSPNPSKRAGSINWSFPDKIKSPRTVRKLSMKMKKLPE 903

  Fly    38 LYKLQL--------EAPAPCPLRCQRTLPLPPAKSTAEAVEANNLAGRLYGSEYHGLMGHLEAEQ 94
            |.:.:.        .||:.....||.........|:..|..|   |.|...|.|| |...:.::|
 Frog   904 LSRKRSIKGTSNADHAPSVSKSNCQDISHTASLSSSGNATAA---ASRNVISRYH-LDSSVSSQQ 964

  Fly    95 LLANARDGSYFVRRSPQSDGYYTLSLRFNKRPKHYKLLYKPGVGHYLRGQDKR----------FD 149
            .......||   .:|....||    |.....|   :|:.|.|    ..|.|.|          .:
 Frog   965 NYKKKNSGS---SKSSSKGGY----LSDGDSP---ELIAKSG----KHGADNRATKGKEALAGSN 1015

  Fly   150 TVHDMVADGLINFHMQLHASPIIQQINQQTKNCYQQ-SPYMTLN--GRKLRALSNELGKAAAKES 211
            |..|:..|...::           ..:.|.| |:|. |..|:|:  |
 Frog  1016 TKSDIDIDAFRHY-----------SFSDQPK-CFQYISGLMSLHFYG------------------ 1050

  Fly   212 KESPAEEKEQKQEEPPPPAVD--------------------------------PMPLVYEKPHHF 244
                       .|:..||.:|                                ...:..|...|.
 Frog  1051 -----------AEDLKPPKIDSKDVFCAIQVDSVNKARTALLTCRTTFLDMDHTFNIELENAQHL 1104

  Fly   245 KVHTFKGLNWCEFCANFLWGFTAQGVKCEAC--GFV----------AHSKCSELVPPKCV----- 292
            |:..|.            |..|.:  |...|  |.|          .|....:|.|...:
 Frog  1105 KLVVFS------------WDPTPR--KNRVCCHGTVVLPALFRVTKTHQLAVKLEPRGLIYVKLN 1155

  Fly   293 -----------PDLKRIRGVFGTDLTTMVQLE-PHHQIPFVVRRCVEEVEARGMLQEGIYRVSGF 345
                       |.:.|...|||.:...:|:.| ....:|.::.:|:.|:|.||....|:||:.|.
 Frog  1156 LMEQWENSLDRPGVDREPIVFGVEARKVVEKENAGLMVPLLMDKCITEIEKRGCQVVGLYRLCGS 1220

  Fly   346 ADEIEALKLALDREGEKTDMSETAYGNVNVIAGTLKLYLRLLPVPLITFQAY----------PSF 400
            |...:.|:.|.:|:.:...:.|:.|.::|||.|.||.|||.||.||||...|          |..
 Frog  1221 AAVKKELREAFERDSKSVGLCESQYPDINVITGVLKDYLRELPSPLITKHLYEAVLKAMAEKPLK 1285

  Fly   401 MAAGRTGKQAEQRQLMAEAVRRLPPAHHSCLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLIA 465
            ||:......:...:.....:..||....:.|:.:|:|||.|||::.||||...|||..|.|.|::
 Frog  1286 MASSGCENDSRDSENTVSLLDCLPDVEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLS 1350

  Fly   466 TPQHMTNLTEEIFM----LSSLITHCKTI 490
            ..|..::....:|:    |:|.:...|.|
 Frog  1351 QRQETSSHNNRVFIDSEELASALDFKKHI 1379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215	23/100 (23%)
		C1_1	242..294	CDD:278556	12/79 (15%)
		RhoGAP_chimaerin	302..491	CDD:239837	65/204 (32%)
syde2	XP_002931720.3	C2	1041..1156	CDD:417471	21/157 (13%)
		RhoGAP	1176..1390	CDD:413382	65/204 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1300981at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920