DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP5A and arhgap9

DIOPT Version :9

Sequence 1:	NP_727007.1	Gene:	RhoGAP5A / 31473	FlyBaseID:	FBgn0029778	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_012813282.2	Gene:	arhgap9 / 100494875	XenbaseID:	XB-GENE-1013568	Length:	789	Species:	Xenopus tropicalis

Alignment Length:	209	Identity:	66/209 - (31%)
Similarity:	106/209 - (50%)	Gaps:	19/209 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   301 VFGTDLTTMVQLEPHHQIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDRE------ 359
            |||..|..:...| :..:|..|..|:|.|..||:..:|||||:|....|:.|:..:|||
Frog   572 VFGCRLDALCHRE-NSTVPKFVCMCIEAVNERGLEADGIYRVNGNLATIQKLRFIVDRERAVTTD 635

  Fly   360 -----------GEKTDMSETAYGNVNVIAGTLKLYLRLLPVPLITFQAYPSFMAAGRTGKQAEQR 413
                       .||.|:|.:.:.:|:||.|.||::.|.||.|||.|..:..::.|.:.....|:.
Frog   636 GRYLFPEQLSQEEKLDLSTSDWEDVHVITGALKMFFRELPEPLIPFSMFEQYVEAVQIPDLDERI 700

  Fly   414 QLMAEAVRRLPPAHHSCLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLIATPQHM-TNLTEEI 477
            :.:.:.|..||..:|..|::||.|||||..|...|:|...|:..||.|||:...:.: :|:...:
Frog   701 ETIKDLVSTLPEPNHDTLKHMLSHLKRVMEHSETNRMTTQNIGIVFGPTLMRPEKELFSNIAANM 765

  Fly   478 FMLSSLITHCKTIF 491
            ...:.::.|..|.:
Frog   766 VYQNQVVEHFLTYY 779

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215
		C1_1	242..294	CDD:278556
		RhoGAP_chimaerin	302..491	CDD:239837	65/206 (32%)
arhgap9	XP_012813282.2	SH3	33..80	CDD:418401
		WW	215..243	CDD:395320
		PH_ARHGAP9-like	379..490	CDD:270053
		RhoGAP_ARHGAP27_15_12_9	573..777	CDD:239868	64/204 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1300981at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010