Protein Alignment RhoGAP5A and syde2

DIOPT Version :9

• Sequence 1: NP_727007.1
• Gene: RhoGAP5A / 31473
• FlyBaseID: FBgn0029778
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_017209238.1
• Gene: syde2 / 100333199
• ZFINID: ZDB-GENE-121116-6
• Length: 719
• Species: Danio rerio
• Alignment Length: 549
• Identity: 126/549 - (22%)
• Similarity: 192/549 - (34%)
• Gaps: 168/549 - (30%)

  Fly    20 VGGAPEPSSPVQKVW-KPELYKLQLEAPAPC-PLRCQRTLPLPPAKSTAEAVEANNLAGRLYGSE 82
            |.|.|..:.||..:. :|..:..::...|.. |.|      ||||..|. |:.:.|:..|
Zfish    15 VKGNPINNVPVNNIQSEPRAHSPRVNGMADLGPSR------LPPAGVTT-ALASGNVIWR----- 67

  Fly    83 YHGLMGHLEAEQLLANARDGSYFVRRSPQSDGYYTLSLRFNKRPKHYKLLYKPGVGHYLRGQDKR 147
            || |...:..:......|..|..|.:|....||    |.....|   :|:.|.|
Zfish    68 YH-LDSSVSTQHSFDKRRSNSAGVPKSASKGGY----LSDGDSP---ELVAKSG----------- 113

  Fly   148 FDTVHDMVADGLINFHMQLHASPIIQQINQQTKNCYQQSPYMTLNGRKLRALSNELGKAAAKESK 212
                                     :..|.:.|||..:.|.......||.....::....:....
Zfish   114 -------------------------KHTNSERKNCKTRDPNGNGGSPKLPGTELDIDAFRSYSFT 153

  Fly   213 ESP----------------AEEKEQKQEEPPPPAVDPMPLV------------------------ 237
            |.|                ||:.:.       |.||...:.
Zfish   154 EQPKCLTYISGLMSLHFYGAEDLKL-------PRVDSRDIYCAIQVDSVNKARTALLTCRTSFLD 211

  Fly   238 --------YEKPHHFKVHTFKGLNWCEFCANFLWGFTAQ--GVKCEAC----GFVAHSKCSEL-- 286
                    .|...|.|:..|.            |..|.:  .|.|...    |....||..:|
Zfish   212 MDHTFNIELENAQHLKLVVFS------------WESTPRRNRVCCHGTVVLPGLFRVSKTHQLAV 264

  Fly   287 -VPPKCV-------------------PDLKRIRGVFGTDLTTMVQLEPHH-QIPFVVRRCVEEVE 330
             :.|:.:                   |.::    |||.:...:|:.|... .:|.::.:|:.|:|
Zfish   265 RLEPRGMIYVKLSLMEQRQNSLDGDHPQMQ----VFGVEARHVVEREASGLMVPLLIEKCISEIE 325

  Fly   331 ARGMLQEGIYRVSGFADEIEALKLALDREGEKTDMSETAYGNVNVIAGTLKLYLRLLPVPLITFQ 395
            .||....|:||:.|.|...:.|:.|.:|:....::||:.|.::|||.|.||.|||.||.||||.|
Zfish   326 RRGCQVVGLYRLCGSAAVKKELREAFERDSHSVELSESNYPDINVITGVLKDYLRELPHPLITQQ 390

  Fly   396 AYPSFMAA--------GRTG--KQAEQRQLMAEAVRRLPPAHHSCLQYMLEHLKRVASHYAVNKM 450
            .|...:.|        |..|  ......||....:..||....:.|:.:|:||||||||:.:|||
Zfish   391 LYECVLEAMMKRPLLMGNAGCENTPADSQLTVSLLDILPDVEKASLKKLLDHLKRVASHHELNKM 455

  Fly   451 NEHNLATVFAPTLIATPQHMTNLTEEIFM 479
            ...|||..|.|.|::..|..::..:.:|:
Zfish   456 PCQNLAVCFGPVLLSQRQEASSQAKRVFI 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215	15/90 (17%)
		C1_1	242..294	CDD:278556	12/79 (15%)
		RhoGAP_chimaerin	302..491	CDD:239837	66/189 (35%)
syde2	XP_017209238.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1300981at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920