Protein Alignment RhoGAP5A and arhgap45

DIOPT Version :9

• Sequence 1: NP_727007.1
• Gene: RhoGAP5A / 31473
• FlyBaseID: FBgn0029778
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_012822956.2
• Gene: arhgap45 / 100125789
• XenbaseID: XB-GENE-990078
• Length: 1114
• Species: Xenopus tropicalis
• Alignment Length: 444
• Identity: 112/444 - (25%)
• Similarity: 178/444 - (40%)
• Gaps: 135/444 - (30%)

  Fly   161 NFHMQLHASPI---------------------IQQIN--QQTKNCYQQSPYM-------TLNGRK 195
            :.|||....|:                     ::|:.  .:.:..|...||.       .:..||
 Frog   497 SMHMQTAPLPVGFQTLCESSKLYDLGQQYASYVRQLGAVNEPETTYDFQPYTPQITWSPCIRSRK 561

  Fly   196 LRALSNELGKAAAKESKESPAEEK---------EQKQEEPP------PPAV-------------- 231
            ....|.::   .:.|:||...||:         .|..:..|      .|||
 Frog   562 SSFNSQDI---PSSENKEISGEERVVERRGGRGHQVHKSWPTAITEGDPAVSNTGTAFPEKLHQP 623

  Fly   232 -DPMPLVYEK-------------------PHH---FK---------VHTFKGL---NWCEFCANF 261
             .|:.:|.:|                   ||.   |:         .|..:.|   :.|..|.::
 Frog   624 SSPIDIVDQKRLSASFEQSINGLSGSLEVPHSTGPFRNIGLSRAALTHRLRKLRTPSKCRECNSY 688

  Fly   262 LWGFTAQGVKCEACGFVAHSKCSELVPPKCVPDLKRIRG---VFGTDLTTMVQLEPHHQIPFVVR 323
            ::   .||.:||.|....|.||.|.:..:|  ..|:::|   :||.|.:......|.| |||::|
 Frog   689 VY---FQGAECEECSLACHKKCLETLAIQC--GHKKLQGRLLLFGRDFSETALRSPDH-IPFLIR 747

  Fly   324 RCVEEVEARGMLQEGIYRVSGFADEIEALKLALDREGEKTDMSETAYGNVNVIAGTLKLYLRLLP 388
            :||.|:|.|.:..:|||||:|....:|.|..|.:...|..::|:   .:.:.::..||||||.||
 Frog   748 KCVSEIEERALTMKGIYRVNGVKTRVEKLCQAFENGKELVELSQ---ASPHDLSNVLKLYLRQLP 809

  Fly   389 VPLITFQAYPSFMAAGR-------TGK---------QAEQRQL-----MAEAVRRLPPAHHSCLQ 432
            .|||.|:.|...|...:       |||         ..|...|     :.|.::.||..:.:.||
 Frog   810 EPLIPFRLYNGLMGLAKESLRGIETGKGSRLQDKGPNTEPEVLSMVVQLKELLQDLPVENRTTLQ 874

  Fly   433 YMLEHLKRVASHYAVNKMNEHNLATVFAPTLIATPQHMTNLTEEIFMLSSLITH 486
            |:::||.||:....:|||:..||..||.|.|: .|:.    |:....||||:.:
 Frog   875 YLVKHLCRVSEQEQLNKMSPSNLGIVFGPALM-RPRP----TDATVSLSSLVDY 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215	2/4 (50%)
		C1_1	242..294	CDD:278556	16/66 (24%)
		RhoGAP_chimaerin	302..491	CDD:239837	69/206 (33%)
arhgap45	XP_012822956.2	PRK12495	<22..151	CDD:183558
		BAR	289..515	CDD:416402	4/17 (24%)
		C1_GMIP-like	669..719	CDD:410366	14/54 (26%)
		RhoGAP	727..936	CDD:413382	69/206 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1300981at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920