Protein Alignment RhoGAP5A and chn1

DIOPT Version :9

• Sequence 1: NP_727007.1
• Gene: RhoGAP5A / 31473
• FlyBaseID: FBgn0029778
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_012825384.1
• Gene: chn1 / 100038142
• XenbaseID: XB-GENE-852930
• Length: 459
• Species: Xenopus tropicalis
• Alignment Length: 453
• Identity: 185/453 - (40%)
• Similarity: 265/453 - (58%)
• Gaps: 53/453 - (11%)

  Fly    33 VWKPELYKLQLEAPAPCPLRCQRTLPLPPAKSTAEAVEANNLAGRLYGSEYHGLMGHLEAEQLLA 97
            |||..||:||.|||.|..:.|.|.:...|               :.||.|:.|::...|.:|||:
 Frog    15 VWKSYLYQLQQEAPHPRRITCTREVFNRP---------------KYYGREFFGMISREETDQLLS 64

  Fly    98 NARDGSYFVRRSPQSDGYYTLSLRFNKRPKHYKLLYKPGVGHYLRGQDKRFDTVHDMVADGLINF 162
            .| :|||.:|.|.:..|.|||:|||..:.::::|.|.   |.:..| :|||:::||:|.||||..
 Frog    65 GA-EGSYLIRESQRQPGTYTLALRFGNQTRNFRLYYD---GKHFVG-EKRFESIHDLVTDGLITL 124

  Fly   163 HMQLHASPIIQQINQQTKN-CYQQSPYMTLNGRKLRALSNELGKAAAKES---KESPAE----EK 219
            :::..|:   :.|.:.|.| .|:...|.|||    |..:::....|.:|:   ||.|.|    ||
 Frog   125 YIETKAA---EYIAKMTINPIYEHIGYTTLN----REPAHKKQMPALREAHVEKECPGEDGISEK 182

  Fly   220 E---------QKQEEPPPPAVDPMPLVYEKPHHFKVHTFKGLNWCEFCANFLWGFTAQGVKCEAC 275
            .         .|:.|..|.        |||.|:||||||:|.:|||:||||:||..||||||..|
 Frog   183 RLTSLVRRATLKENEQVPK--------YEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADC 239

  Fly   276 GFVAHSKCSELVPPKCVPDLKRIRGVFGTDLTTMVQLEPHHQIPFVVRRCVEEVEARGMLQEGIY 340
            |...|.:||::||..|.||||.::.|:..||||:|:.. :.:.|.||..|:.|:|:||:..||:|
 Frog   240 GLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAH-NTKRPMVVDMCIREIESRGLSSEGLY 303

  Fly   341 RVSGFADEIEALKLALDREGEKTDMSETAYGNVNVIAGTLKLYLRLLPVPLITFQAYPSFMAAGR 405
            |||||.|.||..|:|.||:|||.|:|...|.::|:|.|.||||.|.||:|:||:.|||.|:.:.:
 Frog   304 RVSGFTDLIEDAKMAFDRDGEKADISVNVYEDINIITGALKLYFRELPIPIITYDAYPKFLESAK 368

  Fly   406 TGKQAEQRQLMAEAVRRLPPAHHSCLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLIATPQ 468
            ......|.:.:.:|::.|||||...|:|::.|||||..|...|.|:..||..||.|||:..|:
 Frog   369 APDPDAQLETLHDALKLLPPAHCETLRYLMAHLKRVTLHEKDNLMSAENLGIVFGPTLMRAPE 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215	35/90 (39%)
		C1_1	242..294	CDD:278556	31/51 (61%)
		RhoGAP_chimaerin	302..491	CDD:239837	76/167 (46%)
chn1	XP_012825384.1	SH2_a2chimerin_b2chimerin	42..128	CDD:198215	36/105 (34%)
		C1_1	206..255	CDD:365894	30/48 (63%)
		RhoGAP_chimaerin	266..459	CDD:239837	76/167 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	155	1.000	Domainoid score	I4181
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	324	1.000	Inparanoid score	I2457
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1300981at2759
OrthoFinder	1	1.000	-	-		FOG0001164
OrthoInspector	1	1.000	-	-		otm48963
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2268
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060