DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34435 and MYL3

DIOPT Version :9

Sequence 1:	NP_572233.2	Gene:	CG34435 / 31471	FlyBaseID:	FBgn0085464	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_000249.1	Gene:	MYL3 / 4634	HGNCID:	7584	Length:	195	Species:	Homo sapiens

Alignment Length:	175	Identity:	47/175 - (26%)
Similarity:	74/175 - (42%)	Gaps:	29/175 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 EIPKLRNIFDLFVVNECDQAAGGEDVAAPTCLDLGIGIRMTDVADCLRIMGLNPSDDELQQRLEE 92
            :|.:.:..|.||     |:        .|.|   .:.|......|.||.:|.||:..|:.:.|.:
Human    50 QIEEFKEAFMLF-----DR--------TPKC---EMKITYGQCGDVLRALGQNPTQAEVLRVLGK 98

  Fly    93 HVRRRESLGMGMKKIAQRATFELVLTLYCQLAEQEVKEMAKGCIVENVLRVLRSRDSAGTGMLPY 157
              .|:|.|...|      ..||..|.:.     |.:.:.......|:.:..||..|..|.|.:..
Human    99 --PRQEELNTKM------MDFETFLPML-----QHISKNKDTGTYEDFVEGLRVFDKEGNGTVMG 150

  Fly   158 SQLRHLLTTMGNRLDETEVYGVLHRAADINGNVLYEHLVHQLFAT 202
            ::|||:|.|:|.||.|.||..::....|.||.:.||..|..:.::
Human   151 AELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMSS 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34435	NP_572233.2	FRQ1	17..205	CDD:227455	47/175 (27%)
CG34435	NP_572233.2	FRQ1	<188..297	CDD:227455	4/15 (27%)
MYL3	NP_000249.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
MYL3	NP_000249.1	PTZ00184	44..194	CDD:185504	47/172 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23048
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010