DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Vsx1 and sv

DIOPT Version :9

Sequence 1:	NP_001284898.1	Gene:	Vsx1 / 31470	FlyBaseID:	FBgn0263511	Length:	837	Species:	Drosophila melanogaster
Sequence 2:	NP_524633.3	Gene:	sv / 43825	FlyBaseID:	FBgn0005561	Length:	844	Species:	Drosophila melanogaster

Alignment Length:	586	Identity:	108/586 - (18%)
Similarity:	180/586 - (30%)	Gaps:	208/586 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   321 HHAHA-QAHAHAHAHVHAHAAHAA-----------------HAAHAH-AHHAEAFLGAAGGAGGN 366
            ||.|. ..|...|..:|.|..|:.                 |....| .||.:..:        :
  Fly    11 HHIHGLGTHELQHRILHPHILHSTQEETLNTSTGQLEHDSQHLQQHHLTHHQQQDV--------S 67

  Fly   367 P--NSLLAAHGGDVLVGPGGTGPGGKKKNKRRHGR------TIFTSSQLEELEKAFKEAHYPDVS 423
            |  ::|.....||.|.....|       |:.:||.      .::||||:|:..||.|   |.:.|
  Fly    68 PTLHNLQNTRTGDSLSTTINT-------NQNQHGHQHLSGSNMYTSSQMEDKSKANK---YDEYS 122

  Fly   424 ARELLSMK----TGLAEDRIQVWYQNRRAKW--------RKTEKCWGHSTKMAEYG--------L 468
            :|.|.::.    |..|.:.|.   |::..:|        ...|.  .||::.:..|        |
  Fly   123 SRTLSNISDANTTPSANNFIT---QSQGIEWITAMNDIQNGAED--SHSSQGSISGDGHGGVNQL 182

  Fly   469 YGAMVRHSLPLPET-------------------------------IIKSAKEDESVAPWLLGMHK 502
            .|..| :..|||:.                               |:....|..|....::|..|
  Fly   183 GGVFV-NGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSK 246

  Fly   503 KSLEAAELLKSDES-DRETPTS-----DDTNTSYSAGSTHNSPISSFSISRLLFDAPPPAAGSAG 561
            ..:....::.:..: .||.||.     .|...:.:..|..|.| |..||:|::       ...|.
  Fly   247 PKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVP-SVSSINRIV-------RNKAA 303

  Fly   562 GKGHHHHHH--HH-----KGHH----------------------------HAHVHAQAQAHAHML 591
            .|..|.|||  ||     .|.|                            :.:|.|.|..||.:
  Fly   304 EKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSASASVHASI- 367

  Fly   592 LHHQQQQQQQQQQQQHHHHLHAAE----NSLQQQQVAGTGSGSGSGSGSGTGAGSTGPPAHHPYN 652
               ........|....|.:.::.|    ||..:|:..|.......|...|          ||.:|
  Fly   368 ---PTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHG----------HHSHN 419

  Fly   653 QQQHLHHLQQLQQQQQQQQQQAQQQQQHHHHQHHHSVHHMH----------------HHNAAAG- 700
            ...:    ..:......:....:::.:.|...|..::|..:                :.|..:|
  Fly   420 NNNN----SSVNNNNNTESSCKRKRIEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIWSGK 480

  Fly   701 ---------YAEAAVAAAAAAAAVAAAANARNAAAAAAVAAASASAS---------AAVTIAESE 747
                     .||.....|:.....|....|.|..:...::.:.|:||         :..||::::
  Fly   481 WCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDSITTISQTQ 545

  Fly   748 A 748
            :
  Fly   546 S 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vsx1	NP_001284898.1	Homeobox	399..451	CDD:278475	17/69 (25%)
sv	NP_524633.3	PAX	175..299	CDD:128645	23/132 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450976
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930