Protein Alignment Vsx1 and lab

DIOPT Version :10

• Sequence 1: NP_572232.2
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 673
• Identity: 150/673 - (22%)
• Similarity: 212/673 - (31%)
• Gaps: 277/673 - (41%)

  Fly    22 QQQATASATPSEAP----PSPAA--TPPPTANTPANGSLSAVQQQQQQQQQQQQQ---------- 70
            ||..|.:...|.:|    |...|  |||||:      |...|||.|||||.||||
  Fly    63 QQHLTYNGYESSSPGNYYPQQQAQLTPPPTS------SHQVVQQHQQQQQAQQQQLYPHSHLFSP 121

  Fly    71 ----------------QQQLQQQQQQAIDSLRESRS------------ISPDVSRLSAAAAAAAA 107
                            ...|........||..||.|            ::|. |..|...||.|:
  Fly   122 SAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESDSVHSYYATAAVATVAPP-SNSSPITAANAS 185

  Fly   108 AAAHC-----QLPVFNPAN---------FYAAA-------GYAAAADPGNAAAAH---------- 141
            |.::.     |..:.:..|         .|..|       |||...:...||..|
  Fly   186 ATSNTQQQQQQAAIISSENGMMYTNLDCMYPTAQAQAPVHGYAGQIEEKYAAVLHASYAPGMVLE 250

  Fly   142 ---------------HHH-----------MTTLAAAAYLRGFLPPGF-----STPHEFRGHFQQ- 174
                           ||.           |.:|...|::...||.|.     :.||:.:...||
  Fly   251 DQDPMMQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLANNPHQQQPQVQQQ 315

  Fly   175 ----HFGAQFA--EQAAARGQEYASSLANASGDEQ-------SPSKNSSSSGNGGSGGSGSGSGG 226
                |...|..  :..||..|.:.:|::...|..:       ||..::|||.:..:|...:.:..
  Fly   316 QQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQS 380

  Fly   227 GNPT--------------------------SNGLGHL------GSPTASNGGSGGGAGVGGSGGG 259
            .:|.                          ::|:..:      |......||.|||:|||....|
  Fly   381 KSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVG 445

  Fly   260 SGTSGSNSSTSGNGGNGGSSGSRSSPAGPHHSAALAAHQHAAAAAAAAHHHAAAAAAAHHAHHAH 324
            .|.:||    .|.||          .....:|..:|   ::||||.:||.:...
  Fly   446 VGGNGS----PGIGG----------VLSVQNSLIMA---NSAAAAGSAHPNGMG----------- 482

  Fly   325 AQAHAHAHAHVHAHAAHAAHAAHAHAHHAEAFLGAAGGAGGNPNSLLAAHGGDVLVGPGGTGPGG 389
                                            :|...|:|.:..||
  Fly   483 --------------------------------VGLGSGSGLSSCSL------------------- 496

  Fly   390 KKKNKRRHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTE 454
             ..|....|||.||:.||.||||.|....|...:.|..::....|.|.::::|:||||.|.:|..
  Fly   497 -SSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRV 560

  Fly   455 KCWGHSTKMAEYGLYGA--MVRHSLPLPETIIKSAKEDESVAPWLLGMHKKSLEAAEL-LKSDES 516
            |          .||..|  :.:||     |.:.|.|..:...|          :..|| |||..|
  Fly   561 K----------EGLIPADILTQHS-----TSVISEKPPQQQQP----------QPPELQLKSQGS 600

  Fly   517 D----------RETPTSDDTNTS 529
            |          ..|||:..|.|:
  Fly   601 DLGGNELATGAPSTPTTAMTLTA 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx1	NP_572232.2	Homeodomain	395..452	CDD:459649	22/56 (39%)
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	21/52 (40%)