Protein Alignment Vsx1 and pitx3

DIOPT Version :10

• Sequence 1: NP_572232.2
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_991238.1
• Gene: pitx3 / 402974
• ZFINID: ZDB-GENE-041229-4
• Length: 293
• Species: Danio rerio
• Alignment Length: 176
• Identity: 60/176 - (34%)
• Similarity: 84/176 - (47%)
• Gaps: 16/176 - (9%)

  Fly   389 GKKKNKRRHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKT 453
            |..|.|:|..||.|||.||:|||..|:...|||:|.||.:::.|.|.|.|::||::||||||||.
Zfish    54 GSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKR 118

  Fly   454 EKCWGHSTKMAEYGLYGAMVRHSLPLPETIIKSAKEDESVAPWLLGMHKKSLEAAELLKSDESDR 518
            |:  ....::.:.| :||.. :.|..|...:.|.   .|...|.    .|||.::.|     |.:
Zfish   119 ER--NQQAELCKNG-FGAQF-NGLMQPYDDMYSG---YSYNNWA----TKSLASSPL-----SAK 167

  Fly   519 ETPTSDDTNTSYSAGSTHNSPISSFSISRLLFDAPPPAAGSAGGKG 564
            ..|..:..|.|..:.....||.||.....:.....|.|.....|.|
Zfish   168 SFPFFNSMNVSPLSSQPMFSPPSSIPSMNMASSMVPSAVAGVPGSG 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx1	NP_572232.2	Homeodomain	395..452	CDD:459649	30/56 (54%)
pitx3	NP_991238.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..69		7/14 (50%)
		Homeodomain	61..117	CDD:459649	30/55 (55%)
		OAR	251..268	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	255..268
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:O35160	260..264