DRSC/TRiP Functional Genomics Resources

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Protein Alignment Vsx1 and VSX2

DIOPT Version :9

Sequence 1:NP_001284898.1 Gene:Vsx1 / 31470 FlyBaseID:FBgn0263511 Length:837 Species:Drosophila melanogaster
Sequence 2:NP_878314.1 Gene:VSX2 / 338917 HGNCID:1975 Length:361 Species:Homo sapiens


Alignment Length:236 Identity:118/236 - (50%)
Similarity:134/236 - (56%) Gaps:73/236 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   350 AHHAEAFLGAAGGAGGNPNSLLAAH--------GGDVLVGPGG---------------------- 384
            :|...|..|.|      |..||||.        ||..|:||||                      
Human    47 SHPRAALDGLA------PGHLLAARSVLSPAGVGGMGLLGPGGLPGFYTQPTFLEVLSDPQSVHL 105

  Fly   385 ------TGP---------------------------GGKKKNKRRHGRTIFTSSQLEELEKAFKE 416
                  :||                           ..||:.|||| ||||||.|||||||||.|
Human   106 QPLGRASGPLDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRH-RTIFTSYQLEELEKAFNE 169

  Fly   417 AHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTEKCWGHSTKMAEYGLYGAMVRHSLPLPE 481
            ||||||.|||:|:|||.|.|||||||:|||||||||.|||||.|:.||||||||||||||:||||
Human   170 AHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPE 234

  Fly   482 TIIKSAKED--ESVAPWLLGMHKKSLE-AAELLKSDESDRE 519
            :|:||||:.  :|.||||||||||||| |||..:..|.:|:
Human   235 SILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGERQ 275

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Vsx1NP_001284898.1 Homeobox 399..451 CDD:278475 43/51 (84%)
VSX2NP_878314.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..28
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 104..151 6/46 (13%)
Homeobox 153..205 CDD:395001 43/51 (84%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 262..300 5/14 (36%)
OAR 300..318 CDD:397759
OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138 304..317
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 313..361
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0494
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0002963
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR46892
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2566
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
65.900

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