Protein Alignment Vsx1 and unc-4

DIOPT Version :9

• Sequence 1: NP_001284898.1
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_001285389.1
• Gene: unc-4 / 32757
• FlyBaseID: FBgn0024184
• Length: 588
• Species: Drosophila melanogaster
• Alignment Length: 643
• Identity: 157/643 - (24%)
• Similarity: 215/643 - (33%)
• Gaps: 216/643 - (33%)

  Fly   195 LANASGDEQSPSKNSSSSGNGG---------SGGSGSGSGGGNPT---SNGLGHL--GSPTASNG 245
            |.|.:....|.:.||.::.|..         :|.|.|.|....|.   :|...||  |||:::..
  Fly    14 LTNNNNSSASRNNNSHNNNNNNHSPKEIPEETGRSSSTSSNSIPNAHRTNAGQHLLGGSPSSACS 78

  Fly   246 GSGGGAGVGGSG----GGSGTSGSNSSTSGNG------------GNGGSSGSRSSPAGP------ 288
            .|..|.|:...|    .......:.:..:.||            |..|..|    |.||
  Fly    79 TSVSGCGMPSEGLHPTAALQLYAAAAQLAPNGVRVPPWGPFLQFGVPGVFG----PNGPFLGRPR 139

  Fly   289 HHSAALAAHQHAAAAAAAAHHHAAAAAAAHHAHHAHAQAHAHAHAHVHAHAAHAAHAAHAHAHHA 353
            ..:|:...|.::|||||||...||..|:...|:.....|.|..:.......|.||.|:.......
  Fly   140 FDAASAGGHPNSAAAAAAATQMAAVNASNAFANLTGLSAAALRNVSAAQTTAVAAVASTVATIQH 204

  Fly   354 EAFLGAAGGAGGNPNSLLAA----HGGDVLVGPGGTGPGGKKKNKRRHGRTIFTSSQLEELEKAF 414
            ...:       ||..||..|    .|.:...|..|.|.......|||..||.|.|.||||||:||
  Fly   205 RLMI-------GNRQSLPPAGPPSEGSNEDGGFPGDGDDDSSAAKRRRSRTNFNSWQLEELERAF 262

  Fly   415 KEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTEKCWGHSTKMAEYGLYGAMVR--HSL 477
            ..:||||:..||.|:|:..|.|.|:.||:||||||.||.|    |:.|......:.|..:  ...
  Fly   263 SASHYPDIFMREALAMRLDLKESRVAVWFQNRRAKVRKRE----HTKKGPGRPAHNAQPQTCSGE 323

  Fly   478 PLPETIIKS---AKEDESVAPWLLGMHKKSLEA------AELLKSD------------ESDRETP 521
            |:|...:|:   |:..:.:|. .:....:.|:|      .|.||::            :||.|
  Fly   324 PIPPNELKAKERARRRKKLAK-AIDRQARKLQAKGITVDLEALKAEYISQHKANGTFSDSDLE-- 385

  Fly   522 TSDDTNTSYSAGSTHNSPISSFSISRLLFDAPPPAAGSAGGKGHHHHHHHHKGHHHAHVHAQAQA 586
             .|........|:..:....|.::|       |...|..||.|
  Fly   386 -DDGIQIDVVGGTDSDDEGDSDAVS-------PVRLGGGGGGG---------------------- 420

  Fly   587 HAHMLLHHQQQQQQQQQQQQHHHHLHAAENSLQQQQVAGTGSGSGSGSGSGT------------- 638
                                                 .|||.|.|.|:.|..
  Fly   421 -------------------------------------GGTGGGGGGGASSSLHCGLDGDGDSSRA 448

  Fly   639 -----GAGSTGPPAH-----------------HPY--NQQQH----------------LHHLQQL 663
                 |.||.|.|:.                 .|.  |:.:.                ..|...|
  Fly   449 GSFIGGGGSLGSPSSVAPPSMLSNGAVQFGKLEPMDGNESEERDRERDSPKPLLFPAKAFHQLNL 513

  Fly   664 QQQQQQQ-----QQQAQQQQQHHHHQHHHSVHHMHHHNAAAGYAEAAVAAAAAAAAVA 716
            |..||..     |.|.......|.|||:|..||:||.:          |:|:||||||
  Fly   514 QSSQQHHGLVVGQGQGSGSGHGHGHQHNHHQHHLHHGS----------ASASAAAAVA 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx1	NP_001284898.1	Homeobox	399..451	CDD:278475	31/51 (61%)
unc-4	NP_001285389.1	Homeobox	246..299	CDD:278475	31/52 (60%)
		NK	<327..>368	CDD:302627	8/41 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450913
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840