Protein Alignment Vsx1 and Vsx2

DIOPT Version :9

• Sequence 1: NP_001284898.1
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 887
• Identity: 257/887 - (28%)
• Similarity: 323/887 - (36%)
• Gaps: 389/887 - (43%)

  Fly     7 RTPFAIQEILGLGAYQQQATASATPSEAP-----------------PSP----------AATPPP 44
            |:||||||:|||      |.|:||  |||                 |:|          |||...
  Fly     4 RSPFAIQELLGL------AVAAAT--EAPTDLTTTAGATVAKERQTPTPPKTTNATMATAATSAA 60

  Fly    45 TANTPAN---GSLSAVQQQQQQQQQQQQQQQQLQQQQQQAIDSLRESRSISPDVSRLSAAAAAAA 106
            ||.||.|   |:|::|.:.|||.|||||:||
  Fly    61 TAATPTNAAEGNLTSVSEPQQQPQQQQQEQQ---------------------------------- 91

  Fly   107 AAAAHCQLPVFNPANFYAAAGYAAAADPGNAAAAHH--HHMTTLAAAAYLRGFLPPGFSTPHEFR 169
                                              ||  ||                     |::|
  Fly    92 ----------------------------------HHQPHH---------------------HQYR 101

  Fly   170 GHFQQHFGAQFAEQAAARGQEYASSLANASGDEQSPSKNSSSSGNGGSGGSGSGSGGGNPTSNGL 234
            .|.|.       ..|||....|.::
  Fly   102 EHHQM-------TMAAASRMAYFNA---------------------------------------- 119

  Fly   235 GHLGSPTASNGGSGGGAGVGGSGGGSGTSGSNSSTSGNGGNGGSSGSRSSPAGPHHSAALAAHQH 299
                                                                            |
  Fly   120 ----------------------------------------------------------------H 120

  Fly   300 AAAAAAAAHHHAAAAAAAHHAH-HAHAQAHAHAHAHVHAHAA------------HAAHAAHAHAH 351
            ||.|||...|..|||...||.| |.|   |.|.|.| |.|.|            |..|..|....
  Fly   121 AAVAAAFMPHQLAAAVHHHHQHQHQH---HPHHHPH-HPHGAVGGPPPPPPMQHHHPHHPHHPLL 181

  Fly   352 HAEAF---LGAAGGAGG-NPNSLLAAHGGDVLVGPGGTGPGG-KKKNKRRHGRTIFTSSQLEELE 411
            ||:.|   ...|.|||. .|.||.....|...:...|.||.. |||.||||.||||||.|||:||
  Fly   182 HAQGFPQLKSFAAGAGTCLPGSLAPKDFGMESLNGFGVGPNSKKKKKKRRHSRTIFTSYQLEKLE 246

  Fly   412 KAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTEKCWGHSTKMAEYGLYGAMVRHS 476
            :||||||||||.|||:||:||.|.|||||||:||||||||||||.||.||.||||||||||||||
  Fly   247 EAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTEKVWGGSTIMAEYGLYGAMVRHS 311

  Fly   477 LPLPETIIKSAKEDESVAPWLLG-----MHKKSLEAAELLKSDE--SDRE------TPTSDDTNT 528
            ||||:||:||||::::|||||||     ||:||:||...||.|.  ||.|      :..|:|.:.
  Fly   312 LPLPDTILKSAKDNDAVAPWLLGMEQKCMHRKSIEAQSALKDDSGVSDHEDSAGSKSAHSEDLSR 376

  Fly   529 SYS---AGSTHN----SPISSFSISRLLFDAPPPA----AGSAGG-----KGHHHHHHHHKGHHH 577
            |..   :.||.:    ||..|...:.....|||.:    ||:|..     .|            .
  Fly   377 SRCHALSSSTESLNVVSPAPSSCPTSASTSAPPTSTSGYAGAASSAATTPTG------------A 429

  Fly   578 AHVHAQAQAHAHMLLHHQQQQQ----QQQQQQQHHHHLHAAENSLQQQQVAGTGSGSGSGSGSGT 638
            :..::.:..|..:.....||||    |||||||...:|                         |.
  Fly   430 STTNSSSSPHIELGSPSPQQQQHLQLQQQQQQQASLYL-------------------------GA 469

  Fly   639 GAGSTG--PPAHHPY------------NQQQHLHHLQQ------LQQQQQQQQQQAQQQQQHHHH 683
            ||..||  ||::||.            ...:..|.:..      ....|||.|||.|||||
  Fly   470 GAVVTGCAPPSYHPLLDAANAAGAGAAASSKDFHMIMNTAVAAAAAAAQQQHQQQQQQQQQ---- 530

  Fly   684 QHHHSVHHMHHHNAAAGYAEAAVAAAAAAAAVAAAANARNAAAAAAVAAASASASAAVTIAESEA 748
                                        |.|.|...:|.|.|||.......|..:.::....::|
  Fly   531 ----------------------------ATATAPGLHAHNLAAALMEHDPDAFRNNSIACLRAKA 567

  Fly   749 EEEQDDIED-----MELDKDCEVEEDVEPVDNDTNTNNEHDN 785
            :|.|..:.:     :::.:..:.:..::...:....:.||:|
  Fly   568 QEHQARLLNNGGLFLQVRRFAQGQAQIQDPSDMLKLSEEHNN 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx1	NP_001284898.1	Homeobox	399..451	CDD:278475	42/51 (82%)
Vsx2	NP_001284897.1	Homeobox	233..286	CDD:278475	42/52 (81%)
		OAR	556..570	CDD:281777	1/13 (8%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452408
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	1	0.900	-	-		E1_KOG0494
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002963
OrthoInspector	1	1.000	-	-		otm14737
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46892
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2566
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.960