DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vsx1 and rx2

DIOPT Version :9

Sequence 1:	NP_001284898.1	Gene:	Vsx1 / 31470	FlyBaseID:	FBgn0263511	Length:	837	Species:	Drosophila melanogaster
Sequence 2:	NP_571301.2	Gene:	rx2 / 30473	ZFINID:	ZDB-GENE-990415-237	Length:	327	Species:	Danio rerio

Alignment Length:	183	Identity:	63/183 - (34%)
Similarity:	85/183 - (46%)	Gaps:	50/183 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   392 KNKRRHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTEKC 456
            |.|.|..||.||:.||.|||:||:::|||||.:||.|:||..|.|.|:|||:||||||||:.||.
Zfish   132 KKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKM 196

  Fly   457 WGHSTKMAEYGL-----------YGAMVRHSLPLPETIIKSAKEDESVAPWLLGMHKKSLEAAEL 510
            ...:.|:.:..:           .|.| .:||||.              |||    ...|.:|..
Zfish   197 DTGTMKLHDSPIRSFNRPPMAPNVGPM-SNSLPLD--------------PWL----SSPLSSATP 242

  Fly   511 LKS-------DESDRETPTSDDTNTSYSAGSTHN-SPISSFSISRLLFDAPPP 555
            :.|       .:|.:.|.|:.....:.|.|...| .|:            |||
Zfish   243 MHSIPGFMGPGQSLQPTYTAHPGFLNTSPGMMQNMQPM------------PPP 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vsx1	NP_001284898.1	Homeobox	399..451	CDD:278475	33/51 (65%)
rx2	NP_571301.2	Octapeptide motif	37..44
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	48..73
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	100..139		3/6 (50%)
		Homeobox	139..191	CDD:278475	33/51 (65%)
		OAR	302..316	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	304..317
		Nuclear localization signal. /evidence=ECO:0000255	310..314
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	2	1.870