Protein Alignment Vsx1 and RAX

DIOPT Version :10

• Sequence 1: NP_572232.2
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_038463.2
• Gene: RAX / 30062
• HGNCID: 18662
• Length: 346
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 61/200 - (30%)
• Similarity: 78/200 - (39%)
• Gaps: 59/200 - (29%)

  Fly   325 AQAHAHAHAHVHAHAAHAAHAAHAHAHHAEAFLG------------AAGGAGG------------ 365
            |.|.|.....:..|...:...:.:..|..||.||            |..||.|
Human     7 APAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKDDGILGTFPAERGARGAKERDRRLGARP 71

  Fly   366 -------------------------NPNSLLAAHGGDVLVGPG---GTGPGGKK-------KNKR 395
                                     .|........|:....||   |...|..|       |.|.
Human    72 ACPKAPEEGSEPSPPPAPAPAPEYEAPRPYCPKEPGEARPSPGLPVGPATGEAKLSEEEQPKKKH 136

  Fly   396 RHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTEKCWGHS 460
            |..||.||:.||.|||:||:::|||||.:||.|:.|..|.|.|:|||:||||||||:.||....|
Human   137 RRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSS 201

  Fly   461 TKMAE 465
            .|:.:
Human   202 MKLQD 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx1	NP_572232.2	Homeodomain	395..452	CDD:459649	34/56 (61%)
RAX	NP_038463.2	Octapeptide motif	33..40		3/6 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	46..145		17/98 (17%)
		Homeodomain	137..193	CDD:459649	34/55 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..318		4/12 (33%)
		OAR	319..335	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	323..336
		Nuclear localization signal. /evidence=ECO:0000255	329..333