DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vsx1 and Alx4

DIOPT Version :9

Sequence 1:	NP_001284898.1	Gene:	Vsx1 / 31470	FlyBaseID:	FBgn0263511	Length:	837	Species:	Drosophila melanogaster
Sequence 2:	NP_001100023.1	Gene:	Alx4 / 296511	RGDID:	1310201	Length:	399	Species:	Rattus norvegicus

Alignment Length:	289	Identity:	86/289 - (29%)
Similarity:	111/289 - (38%)	Gaps:	59/289 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 YASSLANASGDEQSP---SKNSSSSGNGGSGGSGSGSGGGNPTSNGLGHLGSPTASNGGSGGGAG 252
            |..|.|.|.....||   |:..||...|..||...|:             ...:|:..|.|.|..
  Rat     9 YCESPATAMDAYYSPVSQSREGSSPFRGFPGGDKFGT-------------TFLSAAAKGQGFGDA 60

  Fly   253 VGGSGGGSGTSGSNSSTSGNGGNGGS----SGSRSSPAGPHHSAALAAHQHAAAAAAAAHHHAA- 312
            .|.:..|:|.....:....|.|..||    .....:|..|....|..||.:....|.......:
  Rat    61 KGRARYGAGQQDLAAPLESNAGARGSFNKFQPQPPTPQPPPAPPAPPAHLYLQRGACKTPPDGSL 125

  Fly   313 AAAAAHHAHHAHAQAHAHAHAHVHAHAAHAAHAAHAHAHHAEAFLGAAGGAGGNPNSLLAAHGGD 377
            ........|:|..|...:|                ..::..|..|.......|..||.|:
  Rat   126 KLQEGSGGHNAALQVPCYA----------------KESNLGEPELPPDSEPVGMDNSYLS----- 169

  Fly   378 VLVGPGGTGPGGK----------------KKNKRRHGRTIFTSSQLEELEKAFKEAHYPDVSARE 426
             :...|..||..:                .|.|:|..||.|||.|||||||.|::.|||||.|||
  Rat   170 -VKETGAKGPQDRAGAEIPSPLEKTDSESSKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYARE 233

  Fly   427 LLSMKTGLAEDRIQVWYQNRRAKWRKTEK 455
            .|:|:|.|.|.|:|||:|||||||||.|:
  Rat   234 QLAMRTDLTEARVQVWFQNRRAKWRKRER 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vsx1	NP_001284898.1	Homeobox	399..451	CDD:278475	36/51 (71%)
Alx4	NP_001100023.1	Homeobox	206..258	CDD:278475	36/51 (71%)
Alx4	NP_001100023.1	OAR	375..392	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	3	2.870