Protein Alignment Vsx1 and GSC2

DIOPT Version :10

• Sequence 1: NP_572232.2
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_005306.1
• Gene: GSC2 / 2928
• HGNCID: 4613
• Length: 205
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 71/245 - (28%)
• Similarity: 91/245 - (37%)
• Gaps: 69/245 - (28%)

  Fly   217 SGGSGSGSGGGNPTSNGLGHLGSPTASNGGSGGGAGVGGSGGGSGTSGSNSSTSGNGGNGGSSGS 281
            :||:.|..|.|.|....:.|:.|                       |....|.............
Human     5 AGGAASRRGAGRPCPFSIEHILS-----------------------SLPERSLPARAACPPQPAG 46

  Fly   282 RSSPAGPHHSAALAAHQHAAA------AAAAAHHHAAAAAAAHHAHHAHAQAHAHAHAHVHAHAA 340
            |.|||.|....|..|...|..      ||......|||...|..|....
Human    47 RQSPAKPEEPGAPEAAPCACCCCCGPRAAPCGPPEAAAGLGARLAWPLR---------------- 95

  Fly   341 HAAHAAHAHAHHAEAFLGAAGGAGGNPNSLLAAHGGDVLVGPGGTGPGGKKKNKRRHGRTIFTSS 405
                            ||.|     .|.||.|..||...: ||..|||.:::. ||| ||||:..
Human    96 ----------------LGPA-----VPLSLGAPAGGSGAL-PGAVGPGSQRRT-RRH-RTIFSEE 136

  Fly   406 QLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTEK 455
            ||:.||..|.:..|||||.||.|:.:..|.|:|::||::|||||||..::
Human   137 QLQALEALFVQNQYPDVSTRERLAGRIRLREERVEVWFKNRRAKWRHQKR 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx1	NP_572232.2	Homeodomain	395..452	CDD:459649	31/56 (55%)
GSC2	NP_005306.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..58		6/24 (25%)
		Homeodomain	127..183	CDD:459649	31/56 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	185..205		0/2 (0%)