DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vsx1 and Alx1

DIOPT Version :9

Sequence 1:	NP_001284898.1	Gene:	Vsx1 / 31470	FlyBaseID:	FBgn0263511	Length:	837	Species:	Drosophila melanogaster
Sequence 2:	NP_037053.1	Gene:	Alx1 / 25401	RGDID:	2273	Length:	326	Species:	Rattus norvegicus

Alignment Length:	188	Identity:	69/188 - (36%)
Similarity:	89/188 - (47%)	Gaps:	47/188 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   394 KRRHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTEKCWG 458
            |||| ||.|||.|||||||.|::.|||||..||.|:::|.|.|.|:|||:|||||||||.|:
  Rat   132 KRRH-RTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRER--- 192

  Fly   459 HSTKMAEYGLYGAMVRHSLPLPETIIKSAKEDESVAP------------WLLGMHKKSLEAAELL 511
                   ||.......|.         :|..|.||.|            |.......|:..:.:|
  Rat   193 -------YGQIQQAKSHF---------AATYDISVLPRTDSYPQIQNNLWAGNTSGGSVVTSCML 241

  Fly   512 KSDESDRETPTSDD--TNTSYSAGSTHNS-----PISSFSISRLL--------FDAPP 554
            ..|.|...||.|..  |::||:..|.|.:     |:::|....||        |:..|
  Rat   242 PRDASSCMTPYSHSPRTDSSYTGFSNHQNQFGHVPLNNFFTDSLLTGTTNGHAFETKP 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vsx1	NP_001284898.1	Homeobox	399..451	CDD:278475	34/51 (67%)
Alx1	NP_037053.1	Homeobox	135..188	CDD:278475	35/53 (66%)
		Transactivation domain. /evidence=ECO:0000269\|PubMed:12390248	192..326		27/127 (21%)
		OAR	302..319	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	306..319
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870