Protein Alignment Vsx1 and CRX

DIOPT Version :10

• Sequence 1: NP_572232.2
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_000545.1
• Gene: CRX / 1406
• HGNCID: 2383
• Length: 299
• Species: Homo sapiens
• Alignment Length: 204
• Identity: 64/204 - (31%)
• Similarity: 84/204 - (41%)
• Gaps: 33/204 - (16%)

  Fly   387 PGGKKKNKRRHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWR 451
            |...:|.:|.  ||.||.|||||||..|.:..||||.|||.:::|..|.|.|:|||::|||||.|
Human    33 PSAPRKQRRE--RTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCR 95

  Fly   452 KTEKCWGH------------------------STKMAEYGLYGAMVRHSLPLPETIIKSAKEDES 492
            :..:....                        ||.:....| |....:|.|||...........:
Human    96 QQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPL-GISDSYSPPLPGPSGSPTTAVAT 159

  Fly   493 VAPWLLGMHKKSLEA--AELLKSDESDRETP---TSDDTNTSYSAGSTHNSPISSFS-ISRLLFD 551
            |:.|.........||  |.|:.|..|....|   |....:...|:.|.:.||.|.|| :...|..
Human   160 VSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSP 224

  Fly   552 APPPAAGSA 560
            ..|...|.|
Human   225 MVPQLGGPA 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx1	NP_572232.2	Homeodomain	395..452	CDD:459649	32/56 (57%)
CRX	NP_000545.1	Homeodomain	40..93	CDD:459649	30/54 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..155		10/62 (16%)
		TF_Otx	164..249	CDD:427350	19/70 (27%)