Protein Alignment Vsx1 and Phox2a

DIOPT Version :10

• Sequence 1: NP_572232.2
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_032913.1
• Gene: Phox2a / 11859
• MGIID: 106633
• Length: 280
• Species: Mus musculus
• Alignment Length: 261
• Identity: 75/261 - (28%)
• Similarity: 93/261 - (35%)
• Gaps: 105/261 - (40%)

  Fly   387 PGG-KKKNKRRHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKW 450
            |.| .:|.|:|..||.|||:||:|||:.|.|.||||:..||.|::|..|.|.|:|||:||||||:
Mouse    81 PSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKF 145

  Fly   451 RKTEKCWGHSTKMAEYGLYGAMVRHSLPLPETIIKSAKEDESVAPWLLGMHKKSLEAAELLKSDE 515
            ||.|:  ..|.|    |..||             ..||:.|                |.....|:
Mouse   146 RKQER--AASAK----GAAGA-------------TGAKKGE----------------ARCSSEDD 175

  Fly   516 SDRE---TPTSDDTNTSYSAGSTHNSPISSFSISRLLFDAPPPAAGSAGGKGHHHHHHHHKGHHH 577
            ..:|   :||.|.|      .|....|..|.:..||.....|.|.||..|
Mouse   176 DSKESTCSPTPDST------ASLPPPPAPSLASPRLSPSPLPAALGSGPG--------------- 219

  Fly   578 AHVHAQAQAHAHMLLHHQQQQQQQQQQQQHHHHLHAAENSLQQQQVAG---TGSGSGSGSGSGTG 639
                                                      .|.:.|   .|...|.|.|.|||
Mouse   220 ------------------------------------------PQPLKGALWAGVAGGGGGGPGTG 242

  Fly   640 A 640
            |
Mouse   243 A 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx1	NP_572232.2	Homeodomain	395..452	CDD:459649	33/56 (59%)
Phox2a	NP_032913.1	Homeodomain	91..147	CDD:459649	33/55 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..244		38/197 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..280