DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vsx2 and Vsx1

DIOPT Version :9

Sequence 1:	NP_001284897.1	Gene:	Vsx2 / 31469	FlyBaseID:	FBgn0263512	Length:	645	Species:	Drosophila melanogaster
Sequence 2:	NP_001103016.1	Gene:	Vsx1 / 689704	RGDID:	1305667	Length:	369	Species:	Rattus norvegicus

Alignment Length:	272	Identity:	117/272 - (43%)
Similarity:	141/272 - (51%)	Gaps:	55/272 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 PPPPPPMQHHHPHHPHHPLLHAQGFPQLKSFAAGAGTCLPGSLAPKDFGMESLNGFGVGPNSKK- 225
            |..|.|.....|.||                        |.:|..:..........|..|:.:|
  Rat   115 PAGPEPAVAQSPVHP------------------------PPALGSQQRSENISTSDGDSPSEEKN 155

  Fly   226 ---------KKKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNR 281
                     |:||||| ||:||::|||:||:||.|||||||||||||::||||||||||||||||
  Rat   156 DPKMSLTLGKRKKRRH-RTVFTAHQLEELEKAFGEAHYPDVYAREMLAVKTELPEDRIQVWFQNR 219

  Fly   282 RAKWRKTEKVWGGSTIMAEYGLYGAMVRHSLPLPDTILKSAKD-NDAVAPWLLGMEQKCMHRKSI 345
            ||||||.||.||||::|||||||||||||.:||||::|.||.. ..:.|||||||.:|....:..
  Rat   220 RAKWRKREKRWGGSSVMAEYGLYGAMVRHCIPLPDSVLNSADSLQGSCAPWLLGMHKKSTEMRKP 284

  Fly   346 EAQSAL--------------KDDSGVSDHEDSAGSKSAHSEDLSRSRCHALSSSTESLNVVSPAP 396
            |::..|              ||:.|   .|...|..|.:.|.........||||  |.......|
  Rat   285 ESEEKLAGLWELDHLRKGAKKDEDG---PERGPGKASLNPEGSLEDVAIDLSSS--SRQETKKMP 344

  Fly   397 SSCPTSASTSAP 408
            |...|...|.||
  Rat   345 SGSSTQGCTHAP 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vsx2	NP_001284897.1	Homeobox	233..286	CDD:278475	43/52 (83%)
Vsx2	NP_001284897.1	OAR	556..570	CDD:281777
Vsx1	NP_001103016.1	Homeobox	171..224	CDD:278475	44/53 (83%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	109	1.000	Domainoid score	I6220
eggNOG	1	0.900	-	-		E1_KOG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002963
OrthoInspector	1	1.000	-	-		otm45313
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.770