DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vsx2 and phox2a

DIOPT Version :9

Sequence 1:	NP_001284897.1	Gene:	Vsx2 / 31469	FlyBaseID:	FBgn0263512	Length:	645	Species:	Drosophila melanogaster
Sequence 2:	NP_996953.2	Gene:	phox2a / 404602	ZFINID:	ZDB-GENE-000223-14	Length:	280	Species:	Danio rerio

Alignment Length:	313	Identity:	87/313 - (27%)
Similarity:	120/313 - (38%)	Gaps:	89/313 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 AQGF---PQLKSFAAG-------AGTCLPGSL---APKDFGMESLNGFGVGPNSKKKKKKRRHSR 234
            :.||   |....|::|       ..:|..|:|   .|..:.......|.......:|:|:|| .|
Zfish    33 SNGFQYNPIRSGFSSGPACAPLATASCTLGALREHQPAPYSTVPYKFFSDASGLNEKRKQRR-IR 96

  Fly   235 TIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTEKVWGGSTIMA 299
            |.|||.||::||..|.|.||||:|.||.|:||.:|.|.|:||||||||||:||.|:........:
Zfish    97 TTFTSSQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAANSKASSS 161

  Fly   300 EYGLYGAMVRHSLPLPDTILKSAKDNDAVAPWLLGMEQKCMHRKSIEAQSALKDDSGVSDHEDSA 364
            ..|                                       :|..:|:|:.:||
Zfish   162 SGG---------------------------------------KKPSDARSSSEDD---------- 177

  Fly   365 GSKSAHSEDLSRSRCHALSSSTESLNVVSPAPSSCPTSASTSAPPTSTSGYAGAASSAATTPTGA 429
                    :...|.|.....||  .|:.||       .|.:|..|:...|.|...|.|:.:|
Zfish   178 --------ESKESTCSPTPDST--ANMSSP-------GARSSLSPSPAPGPASTFSPASISP--- 222

  Fly   430 STTNSSSSPHIELGSPSPQQQQHLQLQQQQQQQASLYLGAGAVVTGCAPPSYH 482
             ...||..|.:..|:|.| ...|.|...:..|.|....|..|.|..    |:|
Zfish   223 -ALKSSPWPSLGSGTPGP-THTHTQELLKAWQPADSMSGPFAGVLS----SFH 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vsx2	NP_001284897.1	Homeobox	233..286	CDD:278475	34/52 (65%)
Vsx2	NP_001284897.1	OAR	556..570	CDD:281777
phox2a	NP_996953.2	Homeobox	96..148	CDD:306543	34/51 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810