Protein Alignment Vsx2 and unc-4

DIOPT Version :10

• Sequence 1: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_573242.2
• Gene: unc-4 / 32757
• FlyBaseID: FBgn0024184
• Length: 588
• Species: Drosophila melanogaster
• Alignment Length: 555
• Identity: 135/555 - (24%)
• Similarity: 172/555 - (30%)
• Gaps: 224/555 - (40%)

  Fly    53 ATAATSAATAATPTNA--AEGNLTSVSEPQQQPQQQQQEQQHHQPHHHQYREHHQMTMAAASR-- 113
            :.||.:|||.....||  |..|||.:|                               |||.|
  Fly   151 SAAAAAAATQMAAVNASNAFANLTGLS-------------------------------AAALRNV 184

  Fly   114 -MAYFNAHAAVAA--AFMPHQLAAAVHHHHQHQHQHHPHHHPHHPHGAVGG----PPPPPPMQHH 171
             .|...|.||||:  |.:.|:|                         .:|.    ||..||.:
  Fly   185 SAAQTTAVAAVASTVATIQHRL-------------------------MIGNRQSLPPAGPPSE-- 222

  Fly   172 HPHHPHHPLLHAQGFPQLKSFAAGAGTCLPGSLAPKDFGMESLNGFGVGPNSKKKKKKRRHSRTI 236
                                                  |.....||....:......|||.|||.
  Fly   223 --------------------------------------GSNEDGGFPGDGDDDSSAAKRRRSRTN 249

  Fly   237 FTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTEKVWGG------- 294
            |.|:|||:||.||..:||||::.||.|:::.:|.|.|:.|||||||||.||.|....|
  Fly   250 FNSWQLEELERAFSASHYPDIFMREALAMRLDLKESRVAVWFQNRRAKVRKREHTKKGPGRPAHN 314

  Fly   295 ---STIMAEYGLYGAMVRHSLPLPDTILKS----------AKDNDAVAPWL-----------LGM 335
               .|...|            |:|...||:          ||..|..|..|           |..
  Fly   315 AQPQTCSGE------------PIPPNELKAKERARRRKKLAKAIDRQARKLQAKGITVDLEALKA 367

  Fly   336 EQKCMHR-KSIEAQSALKDDS------GVSDHED---------------------------SAGS 366
            |....|: ....:.|.|:||.      |.:|.:|                           ...|
  Fly   368 EYISQHKANGTFSDSDLEDDGIQIDVVGGTDSDDEGDSDAVSPVRLGGGGGGGGGTGGGGGGGAS 432

  Fly   367 KSAH---SEDLSRSRCHALSSSTESLNVVSPAPSSCPTSASTSAPPTSTSGYAGAASSAATTPTG 428
            .|.|   ..|...||..:......||.           |.|:.|||:..|.  ||.......|..
  Fly   433 SSLHCGLDGDGDSSRAGSFIGGGGSLG-----------SPSSVAPPSMLSN--GAVQFGKLEPMD 484

  Fly   429 ASTTNSSSSPHIELGSPSP-----QQQQHLQLQQQQQQQASLYLGAGAVVTGCAPPSYHPLLDAA 488
            .   |.|.....|..||.|     :....|.||..||.. .|.:|.|.              .:.
  Fly   485 G---NESEERDRERDSPKPLLFPAKAFHQLNLQSSQQHH-GLVVGQGQ--------------GSG 531

  Fly   489 NAAGAGAAASSKDFHMIMNTAVAAAAAA-AQQQHQ 522
            :..|.|...:....|:...:|.|:|||| |...||
  Fly   532 SGHGHGHQHNHHQHHLHHGSASASAAAAVANLVHQ 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx2	NP_001284897.1	Homeodomain	230..287	CDD:459649	33/56 (59%)
		OAR	556..572	CDD:461067
unc-4	NP_573242.2	Homeodomain	244..300	CDD:459649	32/55 (58%)