Protein Alignment Vsx2 and Vsx1

DIOPT Version :10

• Sequence 1: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_572232.2
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Alignment Length: 887
• Identity: 257/887 - (28%)
• Similarity: 323/887 - (36%)
• Gaps: 389/887 - (43%)

  Fly     4 RSPFAIQELLGL------AVAAAT--EAPTDLTTTAGATVAKERQTPTPPKTTNATMATAATSAA 60
            |:||||||:|||      |.|:||  |||                 |:|          |||...
  Fly     7 RTPFAIQEILGLGAYQQQATASATPSEAP-----------------PSP----------AATPPP 44

  Fly    61 TAATPTNAAEGNLTSVSEPQQQPQQQQQEQQ---------------------------------- 91
            ||.||.|   |:|::|.:.|||.|||||:||
  Fly    45 TANTPAN---GSLSAVQQQQQQQQQQQQQQQQLQQQQQQAIDSLRESRSISPDVSRLSAAAAAAA 106

  Fly    92 ----------------------------------HHQPHH---------------------HQYR 101
                                              ||  ||                     |::|
  Fly   107 AAAAHCQLPVFNPANFYAAAGYAAAADPGNAAAAHH--HHMTTLAAAAYLRGFLPPGFSTPHEFR 169

  Fly   102 EHHQM-------TMAAASRMAYFNA---------------------------------------- 119
            .|.|.       ..|||....|.::
  Fly   170 GHFQQHFGAQFAEQAAARGQEYASSLANASGDEQSPSKNSSSSGNGGSGGSGSGSGGGNPTSNGL 234

  Fly   120 ----------------------------------------------------------------H 120
                                                                            |
  Fly   235 GHLGSPTASNGGSGGGAGVGGSGGGSGTSGSNSSTSGNGGNGGSSGSRSSPAGPHHSAALAAHQH 299

  Fly   121 AAVAAAFMPHQLAAAVHHHHQHQHQH---HPHHHPH-HPHGAVGGPPPPPPMQHHHPHHPHHPLL 181
            ||.|||...|..|||...||.| |.|   |.|.|.| |.|.|            |..|..|....
  Fly   300 AAAAAAAAHHHAAAAAAAHHAH-HAHAQAHAHAHAHVHAHAA------------HAAHAAHAHAH 351

  Fly   182 HAQGFPQLKSFAAGAGTCLPGSLAPKDFGMESLNGFGVGPNSKKKKKKRRHSRTIFTSYQLEKLE 246
            ||:.|   ...|.|||. .|.||.....|...:...|.||.. |||.||||.||||||.|||:||
  Fly   352 HAEAF---LGAAGGAGG-NPNSLLAAHGGDVLVGPGGTGPGG-KKKNKRRHGRTIFTSSQLEELE 411

  Fly   247 EAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTEKVWGGSTIMAEYGLYGAMVRHS 311
            :||||||||||.|||:||:||.|.|||||||:||||||||||||.||.||.||||||||||||||
  Fly   412 KAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTEKCWGHSTKMAEYGLYGAMVRHS 476

  Fly   312 LPLPDTILKSAKDNDAVAPWLLGMEQKCMHRKSIEAQSALKDDSGVSDHEDSAGSKSAHSEDLSR 376
            ||||:||:||||::::|||||||     ||:||:||...||.|.  ||.|      :..|:|.:.
  Fly   477 LPLPETIIKSAKEDESVAPWLLG-----MHKKSLEAAELLKSDE--SDRE------TPTSDDTNT 528

  Fly   377 SRCHALSSSTESLNVVSPAPSSCPTSASTSAPPTSTSGYAGAASSAATTPTG------------A 429
            |..   :.||.:    ||..|...:.....|||.:    ||:|..     .|            .
  Fly   529 SYS---AGSTHN----SPISSFSISRLLFDAPPPA----AGSAGG-----KGHHHHHHHHKGHHH 577

  Fly   430 STTNSSSSPHIELGSPSPQQQQHLQLQQQQQQQASLYL-------------------------GA 469
            :..::.:..|..:.....||||    |||||||...:|                         |.
  Fly   578 AHVHAQAQAHAHMLLHHQQQQQ----QQQQQQQHHHHLHAAENSLQQQQVAGTGSGSGSGSGSGT 638

  Fly   470 GAVVTGCAPPSYHPLLDAANAAGAGAAASSKDFHMIMNTAVAAAAAAAQQQHQQQQQQQQQ---- 530
            ||..||  ||::||.            ...:..|.:..      ....|||.|||.|||||
  Fly   639 GAGSTG--PPAHHPY------------NQQQHLHHLQQ------LQQQQQQQQQQAQQQQQHHHH 683

  Fly   531 ----------------------------ATATAPGLHAHNLAAALMEHDPDAFRNNSIACLRAKA 567
                                        |.|.|...:|.|.|||.......|..:.::....::|
  Fly   684 QHHHSVHHMHHHNAAAGYAEAAVAAAAAAAAVAAAANARNAAAAAAVAAASASASAAVTIAESEA 748

  Fly   568 QEHQARLLNNGGLFLQVRRFAQGQAQIQDPSDMLKLSEEHNN 609
            :|.|..:.:     :::.:..:.:..::...:....:.||:|
  Fly   749 EEEQDDIED-----MELDKDCEVEEDVEPVDNDTNTNNEHDN 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx2	NP_001284897.1	Homeodomain	230..287	CDD:459649	46/56 (82%)
		OAR	556..572	CDD:461067	2/15 (13%)
Vsx1	NP_572232.2	Homeodomain	395..452	CDD:459649	46/56 (82%)