DRSC/TRiP Functional Genomics Resources

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Protein Alignment Vsx2 and rx1

DIOPT Version :9

Sequence 1:NP_001284897.1 Gene:Vsx2 / 31469 FlyBaseID:FBgn0263512 Length:645 Species:Drosophila melanogaster
Sequence 2:NP_571300.2 Gene:rx1 / 30472 ZFINID:ZDB-GENE-990415-236 Length:330 Species:Danio rerio


Alignment Length:351 Identity:83/351 - (23%)
Similarity:111/351 - (31%) Gaps:163/351 - (46%)


- Green bases have known domain annotations that are detailed below.


  Fly   222 NSKKKKKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWR 286
            :.::.|||.|.:||.||:|||.:||.||:::||||||:||.|::|..|||.|:||||||||||||
Zfish   129 DGEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWR 193

  Fly   287 KTEKVWGGSTIMAEYGLYGAMVRHSLPLPDTILKSAKDNDAVAPWLLGMEQKCMHRKSIEAQSAL 351
            :.||: ..||          |..|..|                  :|...:..||          
Zfish   194 RQEKI-DAST----------MKLHDSP------------------MLSFNRPSMH---------- 219

  Fly   352 KDDSGVSDHEDSAGSKSAHSEDLSRSRCHALSSSTESLNVVSPAPSSCPTSASTSAPPTSTSGYA 416
                                            .:...:|...|.....|:..|::.|..|..|:.
Zfish   220 --------------------------------PTVGPMNNSLPLDPWLPSPLSSATPVHSIPGFM 252

  Fly   417 GAASSAATTPTGASTTNSSSSPHIELGSPSPQQQQHLQLQQQQQQQASLYLGAGAVVTGCAPP-- 479
            |......|...|          |..|..|.|..|....:.....|              |.||  
Zfish   253 GPTQGLQTGYPG----------HSFLSPPQPMAQSMQPMAPPPYQ--------------CPPPFT 293

  Fly   480 SYHPLLDAANAAGAGAAASSKDFHMIMNTAVAAAAAAAQQQHQQQQQQQQQATATAPGLHAHNLA 544
            ..:||.|...                                                       
Zfish   294 DKYPLEDVDQ------------------------------------------------------- 303

  Fly   545 AALMEHDPDAFRNNSIACLRAKAQEH 570
                       |::|||.||.||:||
Zfish   304 -----------RSSSIAALRMKAKEH 318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Vsx2NP_001284897.1 Homeobox 233..286 CDD:278475 35/52 (67%)
OAR 556..570 CDD:281777 8/13 (62%)
rx1NP_571300.2 Octapeptide motif 37..44
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 66..104
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 118..142 4/12 (33%)
Homeobox 141..193 CDD:278475 35/51 (69%)
OAR 302..318 CDD:281777 8/81 (10%)
OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138 306..319 9/13 (69%)
Nuclear localization signal. /evidence=ECO:0000255 312..316 2/3 (67%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D454642at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
ZFIN 00.000 Not matched by this tool.
32.880

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