Protein Alignment Vsx2 and RAX

DIOPT Version :9

• Sequence 1: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_038463.2
• Gene: RAX / 30062
• HGNCID: 18662
• Length: 346
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 109/432 - (25%)
• Similarity: 139/432 - (32%)
• Gaps: 183/432 - (42%)

  Fly   152 PHHP-HGAVGGPPP-PPPMQHHHPHHPHHPLLHAQGFPQLKSFAAGAGTCLPGSLAPKDFGMESL 214
            |..| .|:...||| |.|...:....|:.|          |.         ||...|..
Human    74 PKAPEEGSEPSPPPAPAPAPEYEAPRPYCP----------KE---------PGEARPSP------ 113

  Fly   215 NGFGVGP--------NSKKKKKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPE 271
             |..|||        ..::.|||.|.:||.||:|||.:||.||:::||||||:||.|:.|..|||
Human   114 -GLPVGPATGEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPE 177

  Fly   272 DRIQVWFQNRRAKWRKTEKVWGGSTIMAEYGLYGAMVRHSLPLPDTILKSAKDNDAVAPWLLGME 336
            .|:||||||||||||:.||
Human   178 VRVQVWFQNRRAKWRRQEK---------------------------------------------- 196

  Fly   337 QKCMHRKSIEAQSALKDDSGVSDHEDSAGSKSAHSEDLSRSRCHALSSSTESLNVVSPAPSSCPT 401
                    :|..|....||.:                ||.||    |..:.:|:.:...|.|...
Human   197 --------LEVSSMKLQDSPL----------------LSFSR----SPPSATLSPLGAGPGSGGG 233

  Fly   402 SASTSAPPTSTSG---YAGAASSAATTPTGASTTNSSSSPHIELGSPSPQQQQHLQLQQQQQQQA 463
            .|..:.|..|..|   ..|.|::..:.|.......|..:.:    :|.|.....|.
Human   234 PAGGALPLESWLGPPLPGGGATALQSLPGFGPPAQSLPASY----TPPPPPPPFLN--------- 285

  Fly   464 SLYLGAGAVVTGCAPPSYHPLLDAANAAGAGAAASSKDFHMIMNTAVAAAAAAAQQQHQQQQQQQ 528
            |..||.|.......||||
Human   286 SPPLGPGLQPLAPPPPSY----------------------------------------------- 303

  Fly   529 QQATATAPGLHAHNLAAALMEHDPDAFRNNSIACLRAKAQEH 570
                ...||.   .....|.|.||   ||:|||.||.||:||
Human   304 ----PCGPGF---GDKFPLDEADP---RNSSIAALRLKAKEH 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx2	NP_001284897.1	Homeobox	233..286	CDD:278475	35/52 (67%)
		OAR	556..570	CDD:281777	9/13 (69%)
RAX	NP_038463.2	Octapeptide motif	33..40
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	46..145		25/96 (26%)
		Homeobox	140..192	CDD:278475	35/51 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..318		36/264 (14%)
		OAR	319..335	CDD:281777	11/18 (61%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	323..336		9/13 (69%)
		Nuclear localization signal. /evidence=ECO:0000255	329..333		2/3 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454642at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920