DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Vsx2 and Alx4

DIOPT Version :9

Sequence 1:NP_001284897.1 Gene:Vsx2 / 31469 FlyBaseID:FBgn0263512 Length:645 Species:Drosophila melanogaster
Sequence 2:NP_001100023.1 Gene:Alx4 / 296511 RGDID:1310201 Length:399 Species:Rattus norvegicus


Alignment Length:456 Identity:111/456 - (24%)
Similarity:153/456 - (33%) Gaps:202/456 - (44%)


- Green bases have known domain annotations that are detailed below.


  Fly   162 PPPPPPMQHHHPHHPHHPLLH-------AQGFPQLKSFAAGAGTCLPGSLAPKD----------- 208
            |||.||..      |.|..|.       ..|..:|:..:.|....|......|:           
  Rat    99 PPPAPPAP------PAHLYLQRGACKTPPDGSLKLQEGSGGHNAALQVPCYAKESNLGEPELPPD 157

  Fly   209 ---FGME----SLNGFGV-GP---------------NSKKKKKKRRHSRTIFTSYQLEKLEEAFK 250
               .||:    |:...|. ||               :|:..|.|:|.:||.|||||||:||:.|:
  Rat   158 SEPVGMDNSYLSVKETGAKGPQDRAGAEIPSPLEKTDSESSKGKKRRNRTTFTSYQLEELEKVFQ 222

  Fly   251 EAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTEKVWGGSTIMAEYGLYGAMVRHSLPLP 315
            :.|||||||||.|:::|:|.|.|:|||||||||||||.|:......:...:.     ..:.||| 
  Rat   223 KTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFS-----TAYELPL- 281

  Fly   316 DTILKSAKDNDAVAPWLLGMEQKCMHRKSIEAQSALKDDSGVSDHEDSAGSKSAHSEDLSRSRCH 380
                                                                      |:|:..:
  Rat   282 ----------------------------------------------------------LTRAENY 288

  Fly   381 ALSSSTESLNVVSPAPSSCPTSASTSAPPTSTSGYAGAAS--SAATTPTGASTTNSSSSPHIELG 443
            |        .:.:|                |..|..||||  .|...|.                
  Rat   289 A--------QIQNP----------------SWIGNNGAASPVPACVVPC---------------- 313

  Fly   444 SPSPQQQQHLQLQQQQQQQASLYLGAGAVVTGCAPPSYHPLLDAANAAGAGAAASSKDFHMIMNT 508
            .|.|                           .|..|..||       .|:||::.| ||     .
  Rat   314 DPVP---------------------------ACMSPHAHP-------PGSGASSVS-DF-----L 338

  Fly   509 AVAAAAAAAQQQHQQQQQQQQQATATAPGLHAHNLAAALMEHDPDAFRNNSIACLRAKAQEHQAR 573
            :|:.|.:...|.|   ......|...:|||:.:.     |..:||. :.:|||.||.||:||.|.
  Rat   339 SVSGAGSHVGQTH---MGSLFGAAGISPGLNGYE-----MNGEPDR-KTSSIAALRMKAKEHSAA 394

  Fly   574 L 574
            :
  Rat   395 I 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Vsx2NP_001284897.1 Homeobox 233..286 CDD:278475 36/52 (69%)
OAR 556..570 CDD:281777 7/13 (54%)
Alx4NP_001100023.1 Homeobox 206..258 CDD:278475 36/51 (71%)
OAR 375..392 CDD:281777 9/17 (53%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D454642at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
43.880

Return to query results.
Submit another query.