Protein Alignment Vsx2 and Prrx1

DIOPT Version :10

• Sequence 1: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_035257.1
• Gene: Prrx1 / 18933
• MGIID: 97712
• Length: 245
• Species: Mus musculus
• Alignment Length: 254
• Identity: 71/254 - (27%)
• Similarity: 107/254 - (42%)
• Gaps: 90/254 - (35%)

  Fly   202 GSLAPKDFGMESLNGFGVGPNSKKKKKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLK 266
            ||..|:. ..:.||      :.:|||:|:|.:||.|.|.||:.||..|:..||||.:.||.|:.:
Mouse    73 GSDTPQQ-DNDQLN------SEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARR 130

  Fly   267 TELPEDRIQVWFQNRRAKWRKTEKVWGGSTIMAEYGLYGAMVRHSLPLPDTILKSAKDNDAVAPW 331
            ..|.|.|:||||||||||:|:.|:               ||:.:         |:|
Mouse   131 VNLTEARVQVWFQNRRAKFRRNER---------------AMLAN---------KNA--------- 162

  Fly   332 LLGMEQKCMHRKSIEAQSALKDDSGVSDHEDSAGSKSAHSEDLSRSRCHALSSSTESLNVVSPAP 396
                             |.||..||                |:         ::.|...|..|||
Mouse   163 -----------------SLLKSYSG----------------DV---------TAVEQPIVPRPAP 185

  Fly   397 SSCPT---SASTSAPPTSTSGYAGAASSAATTPT-GASTTNSSSSPHIELGSPSPQQQQ 451
            .  ||   |..|::|.::.:.|  :|:.|..:|. |.:..||.::..::....|.|:.|
Mouse   186 R--PTDYLSWGTASPYSAMATY--SATCANNSPAQGINMANSIANLRLKAKEYSLQRNQ 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx2	NP_001284897.1	Homeodomain	230..287	CDD:459649	30/56 (54%)
		OAR	556..572	CDD:461067
Prrx1	NP_035257.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	54..103		13/36 (36%)
		Homeodomain	99..151	CDD:459649	28/51 (55%)
		OAR	219..235	CDD:461067	2/15 (13%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	222..235		2/12 (17%)