DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vsx2 and dsc-1

DIOPT Version :9

Sequence 1:	NP_001284897.1	Gene:	Vsx2 / 31469	FlyBaseID:	FBgn0263512	Length:	645	Species:	Drosophila melanogaster
Sequence 2:	NP_510497.1	Gene:	dsc-1 / 181599	WormBaseID:	WBGene00001096	Length:	310	Species:	Caenorhabditis elegans

Alignment Length:	229	Identity:	73/229 - (31%)
Similarity:	103/229 - (44%)	Gaps:	30/229 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 SVSEPQQQPQQQQQEQQHHQPHHHQYREHHQMTMAAASRMAYFNA-HAAVAAAFMPHQLAAAVHH 138
            ||:.....|..||..||.|.|.:        :....|.|.:..:: ||....|...|.|..|:|:
Worm    27 SVTTDFSVPPVQQGAQQFHPPRN--------LGPQLARRWSCGDSQHADEPPASYYHNLGVALHN 83

  Fly   139 HHQHQHQHH-----------PHHHPHHPHGAVGGPPPPPPMQHHHPHHPHHPLLHAQGFPQL--K 190
            |.|..:||:           |....|.    .|..|...|..|.....||....||.|...:  .
Worm    84 HFQMSNQHYLSDFDCPTTVSPISSAHE----TGQLPQLSPYDHIGNQDPHMFSPHAYGNSMIPDN 144

  Fly   191 SFAAGAGTCLPGSLAPKDFGMESLNGFGVGPNSKKKKKKRRHSRTIFTSYQLEKLEEAFKEAHYP 255
            |:...|..    |::..:.|..:||...:..::.:....||..||.||..|...||::|||:|||
Worm   145 SYFENASR----SISAPNVGNSTLNPSLMSSDNAQSCGGRRRFRTNFTELQSTFLEDSFKESHYP 205

  Fly   256 DVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTE 289
            |..|::.::...::|||||.|||||||||||:.|
Worm   206 DHKAKKYMADFLKIPEDRITVWFQNRRAKWRRKE 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vsx2	NP_001284897.1	Homeobox	233..286	CDD:278475	29/52 (56%)
Vsx2	NP_001284897.1	OAR	556..570	CDD:281777
dsc-1	NP_510497.1	Homeobox	184..236	CDD:278475	29/51 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810