Protein Alignment Vsx2 and Phox2a

DIOPT Version :10

• Sequence 1: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_446321.2
• Gene: Phox2a / 116648
• RGDID: 621323
• Length: 281
• Species: Rattus norvegicus
• Alignment Length: 314
• Identity: 90/314 - (28%)
• Similarity: 117/314 - (37%)
• Gaps: 98/314 - (31%)

  Fly   156 HGAVGGPPPPPPMQHHHPHHPHHPLLHAQGFPQLKSFAAGAGTCLPGSL----------APKDFG 210
            :|..|....|...|    :.|..|...|.|.|   ..|.|:..|..|:|          .|..|.
  Rat    21 YGDFGACSQPGGFQ----YSPLRPAFPAAGPP---CPALGSSNCALGALRDHQPAPYSAVPYKFF 78

  Fly   211 MESLNGFGVGPNSKKKKKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQ 275
            .|        |:...:|:|:|..||.|||.||::||..|.|.||||:|.||.|:||.:|.|.|:|
  Rat    79 PE--------PSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQ 135

  Fly   276 VWFQNRRAKWRKTEKVWGGSTIMAEYGLYGAMVRHSLPLPDTILKSAKDNDAVAPWLLGMEQKCM 340
            |||||||||:||.|:   .::.....|..||
  Rat   136 VWFQNRRAKFRKQER---AASAKGAAGATGA---------------------------------- 163

  Fly   341 HRKSIEAQSALKDDSGVSDHEDSAGSKSAHSEDLSRSRCHALSSSTESLNVVSPAPS-SCPTSAS 404
              |..||:.:.:||                  |...|.|.....||.||....|||| :.|..:.
  Rat   164 --KKGEARCSSEDD------------------DSKESTCSPTPDSTASLPPPPPAPSLASPRLSP 208

  Fly   405 TSAPPTSTSG----------YAGAASSAATTP-TGASTTNSSSSPHIELGSPSP 447
            :..|....||          :||.|......| .||:....:..|    ..|.|
  Rat   209 SPLPAALGSGPGPQPLKGALWAGVAGGGGGGPGAGAAELLKAWQP----AEPGP 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx2	NP_001284897.1	Homeodomain	230..287	CDD:459649	35/56 (63%)
		OAR	556..572	CDD:461067
Phox2a	NP_446321.2	Homeodomain	91..147	CDD:459649	35/55 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..219		25/130 (19%)