Protein Alignment Vsx2 and pitx3

DIOPT Version :10

• Sequence 1: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: XP_002935807.2
• Gene: pitx3 / 100496690
• XenbaseID: XB-GENE-486162
• Length: 292
• Species: Xenopus tropicalis
• Alignment Length: 356
• Identity: 83/356 - (23%)
• Similarity: 122/356 - (34%)
• Gaps: 146/356 - (41%)

  Fly   221 PNSKKKKKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKW 285
            |.....|||:|..||.|||.||::||..|:...|||:..||.:::.|.|.|.|::|||:||||||
 Frog    51 PEDGTLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKW 115

  Fly   286 RKTEKVWGGSTIMAEYGLYGAMVRHSLPLPDTILKSAKDNDAVAPWLLGMEQKCMHRKSIEAQSA 350
            ||.|:..........:|                   |:.|..:.|:
 Frog   116 RKRERNQQAELCKNSFG-------------------AQFNGLMQPY------------------- 142

  Fly   351 LKDD--SGVSDHEDSAGSKSAHSEDLSRSRCHALSSSTESLNVVSPAPS----SCPTSASTSAPP 409
              ||  ||.|  .::..:|...:..||.......:|..     |||..|    |.|.|.::...|
 Frog   143 --DDMYSGYS--YNNWATKGLATSPLSAKSFPFFNSMN-----VSPLSSQPMFSPPNSIASMTMP 198

  Fly   410 TSTSGYAGAASSAATTPTGASTTNSSSSPHIELGSPSPQQQQHLQLQQQQQQQASLYLGAGAVVT 474
            :|      ...||.|...|:|..|..:..:  |.|||
 Frog   199 SS------MVPSAVTGVPGSSLNNLGNINN--LNSPS---------------------------- 227

  Fly   475 GCAPPSYHPLLDAANAAGAGAAASSKDFHMIMNTAVAAAAAAAQQQHQQQQQQQQQATATAPGLH 539
                                           :|:||:|:|.             ..|:..:|.::
 Frog   228 -------------------------------LNSAVSASAC-------------PYASTASPYMY 248

  Fly   540 AHNLAAALMEHDPDAFRNNSIACLRAKAQEH 570
            ....             |:|:|.||.||::|
 Frog   249 RDTC-------------NSSLASLRLKAKQH 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx2	NP_001284897.1	Homeodomain	230..287	CDD:459649	29/56 (52%)
		OAR	556..572	CDD:461067	8/15 (53%)
pitx3	XP_002935807.2	Homeodomain	61..117	CDD:459649	29/55 (53%)
		OAR	250..267	CDD:461067	8/30 (27%)