DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vsx2 and rax2

DIOPT Version :9

Sequence 1:	NP_001284897.1	Gene:	Vsx2 / 31469	FlyBaseID:	FBgn0263512	Length:	645	Species:	Drosophila melanogaster
Sequence 2:	XP_002941436.1	Gene:	rax2 / 100494721	XenbaseID:	XB-GENE-494483	Length:	227	Species:	Xenopus tropicalis

Alignment Length:	213	Identity:	66/213 - (30%)
Similarity:	97/213 - (45%)	Gaps:	39/213 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 KDFGMESLNGFGVGPNSKKKKKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPE 271
            ::.|.....|...|.:::..|||.|.:||.||:|||.:||.||:.:||||||:||.|::|..|||
Frog    13 REDGSTPTPGTPEGEDNELPKKKHRRNRTTFTTYQLHELERAFERSHYPDVYSREELAMKVSLPE 77

  Fly   272 DRIQVWFQNRRAKWRKTEKVWGGSTIMAEYGLY----GAMVRHSLPLPDTILKSAKDNDAVAPWL 332
            .|:||||||||||||:.||:...|:.:.:..|.    ..|.....||.:|:        .:.|||
Frog    78 VRVQVWFQNRRAKWRRQEKLETSSSKLHDSPLLSFSRSPMATGVGPLSNTL--------PLEPWL 134

  Fly   333 LGMEQKCMHRKSIEAQSALKDDSGVSDHEDSAGSKSAHSEDLSRSRCHALSSSTESLNVVSPAPS 397
            .                           ....|:.:.||.....:...||..:.:|...::..|.
Frog   135 T---------------------------SPIPGTTTVHSMPAFMAPSQALQPTYQSHTFLNSGPP 172

  Fly   398 SCPTSASTSAPPTSTSGY 415
            ..|....:.||.....|:
Frog   173 MTPIQPLSGAPYQCMGGF 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vsx2	NP_001284897.1	Homeobox	233..286	CDD:278475	35/52 (67%)
Vsx2	NP_001284897.1	OAR	556..570	CDD:281777
rax2	XP_002941436.1	Homeobox	40..93	CDD:365835	36/52 (69%)
rax2	XP_002941436.1	OAR	200..216	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454642at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920