DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vsx2 and lhx3

DIOPT Version :9

Sequence 1:	NP_001284897.1	Gene:	Vsx2 / 31469	FlyBaseID:	FBgn0263512	Length:	645	Species:	Drosophila melanogaster
Sequence 2:	XP_031747852.1	Gene:	lhx3 / 100489308	XenbaseID:	XB-GENE-490075	Length:	403	Species:	Xenopus tropicalis

Alignment Length:	216	Identity:	60/216 - (27%)
Similarity:	95/216 - (43%)	Gaps:	33/216 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 KKKKKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKT 288
            ::.:...:..||..|:.|||.|:.|:..:..|..:.||.||.:|.|....:||||||||||.::.
Frog   156 REAESTAKRPRTTITAKQLETLKNAYNNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRL 220

  Fly   289 EKVWGGSTIMAEYGLYGAMVR----HSLPLPDTILKSAKDNDAVA-----PWLLGMEQKCMHRKS 344
            :|..|    ...:|.|...::    :|....|:|.:...|:||..     |.:..|.    |...
Frog   221 KKDAG----RQRWGQYFRNMKRSRGNSKSDKDSIQEEGPDSDAEVSFTDEPSMSEMN----HSNG 277

  Fly   345 IEAQSALKDDSGVSDHEDSAGSKSAHSEDLSRSRCH-ALSSSTESLNVVSPAPSSCPTS-ASTSA 407
            |  .:::.|.|.|...:  |||....|.:      | .:.:..:..|:.|.:|...|.| ||..:
Frog   278 I--YNSMNDTSPVLGRQ--AGSNGPFSLE------HGGIPTQDQYHNLRSNSPYGIPQSPASLQS 332

  Fly   408 PPTSTSGYAGAASSAATTPTG 428
            .|    |:....|:.|...||
Frog   333 MP----GHQSLLSNLAFPDTG 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vsx2	NP_001284897.1	Homeobox	233..286	CDD:278475	25/52 (48%)
Vsx2	NP_001284897.1	OAR	556..570	CDD:281777
lhx3	XP_031747852.1	LIM1_Lhx3b	33..87	CDD:188851
		LIM2_Lhx3_Lhx4	95..150	CDD:188762
		Homeobox	165..219	CDD:395001	25/53 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1174754at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010