Protein Alignment Vsx2 and shox2

DIOPT Version :10

• Sequence 1: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_001093694.1
• Gene: shox2 / 100101703
• XenbaseID: XB-GENE-480993
• Length: 311
• Species: Xenopus tropicalis
• Alignment Length: 278
• Identity: 84/278 - (30%)
• Similarity: 116/278 - (41%)
• Gaps: 81/278 - (29%)

  Fly   195 GAGTCLPGSLAP---KDFGMESLNGFG------VGPNSKKKKK---------------KRRHSRT 235
            |.|....|:.:|   .|..:|.:...|      |.|..|::|:               |:|.|||
 Frog    61 GGGGGGGGARSPVLELDLSVERIRESGSPKLTEVSPEIKERKEELKQQALEEEGQTKIKQRRSRT 125

  Fly   236 IFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTEK-------VWG 293
            .||..||.:||..|.|.||||.:.||.||.:..|.|.|:||||||||||.||.|.       :..
 Frog   126 NFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGA 190

  Fly   294 GSTI----MAEYGLYGAMVRHSLPLPDTILKSAKDNDAVAPWLLGMEQKCMHRKSIEAQSALKDD 354
            ||..    :|.|...||:   .:|.       .:|:....|.|           |.:.|:.|:.|
 Frog   191 GSQFEACRVAPYVNVGAL---RMPF-------QQDSHCNVPSL-----------SFQVQAQLQLD 234

  Fly   355 SGVSD-HEDSAGSKSAHSEDLSRSRCHALSSSTESLNVVSPAPS-SCPTSASTSAPPTSTSGYAG 417
            |.|:. |.......:||:.                 .::.|||. ..|  .:|.|..|:|:....
 Frog   235 SAVAHAHHHLHPHLTAHAP-----------------YMMFPAPPFGLP--LATLAAETATAASVV 280

  Fly   418 AASSAATTPTGASTTNSS 435
            ||::||.|    |:.|||
 Frog   281 AAAAAAKT----SSKNSS 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vsx2	NP_001284897.1	Homeodomain	230..287	CDD:459649	33/56 (59%)
		OAR	556..572	CDD:461067
shox2	NP_001093694.1	Homeodomain	121..177	CDD:459649	33/55 (60%)
		OAR	292..307	CDD:461067	3/3 (100%)