DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12730 and CMTM4

DIOPT Version :9

Sequence 1:	NP_001284896.1	Gene:	CG12730 / 31466	FlyBaseID:	FBgn0029771	Length:	148	Species:	Drosophila melanogaster
Sequence 2:	NP_848933.1	Gene:	CMTM4 / 146223	HGNCID:	19175	Length:	234	Species:	Homo sapiens

Alignment Length:	147	Identity:	44/147 - (29%)
Similarity:	67/147 - (45%)	Gaps:	25/147 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 DRKYLLSMPGLCKLACLLCSFVGILCI----ICGPVRVSNFRGSFYLAVVTI-GFVATGCLLLAR 69
            |..||....|..|:|.::.:.:..:||    .|.|.     .|.::...|:. .||.||.||:..
Human    46 DPDYLRGALGRLKVAQVILALIAFICIETIMACSPC-----EGLYFFEFVSCSAFVVTGVLLIMF 105

  Fly    70 YLRLWQRQFCRCDPTL-WSLA--VHSSL-ALAYFTASGLVLSLD--IGAYTAAAFFGL---TAFC 125
            .|.|..|     .|.: |:|.  |::.| |..:|.||.::.:|:  .||..||..||.   .|:.
Human   106 SLNLHMR-----IPQINWNLTDLVNTGLSAFLFFIASIVLAALNHRAGAEIAAVIFGFLATAAYA 165

  Fly   126 INGLEAYGNYRRS-RQR 141
            :|...|...:|.| ||:
Human   166 VNTFLAVQKWRVSVRQQ 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12730	NP_001284896.1	None
CMTM4	NP_848933.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..38
CMTM4	NP_848933.1	MARVEL	49..170	CDD:279608	38/130 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4788
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22776
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910