Protein Alignment frma and Nepl19

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Alignment Length: 709
• Identity: 148/709 - (20%)
• Similarity: 264/709 - (37%)
• Gaps: 221/709 - (31%)

  Fly    18 QVKSHPQ--ADPCQNFYKVACGNW-SASHATDSY---ESFMDRLDYNYQEKLADLLDNER--EDD 74
            :::|:.|  ||.|:|||..:|||| ..:.|.|:|   .:|:..|...|..|...|::...  |.|
  Fly    64 EMRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQQRLMEQPANVETD 128

  Fly    75 EPHFLQQLRNFYTACR--KPLSQDQVLRILEHLIV----------------------MENIQNEE 115
            |...| :|:.||.:|.  :.:.:|...|.|:.::.                      ::.:...:
  Fly   129 EVAVL-RLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFDWLDTVARIK 192

  Fly   116 LSVGLTAAFRLQVLID----------LNDSNTYDIWKQLMSH-RKHW--DPN---TTNRE----- 159
            ...|.......|...|          |.::|...:.:.:.:| .:|.  ||.   ||.||
  Fly   193 RQYGFDILLLFQQSADRIYVGQPKQILPEANRKAVAEDIANHLERHLGVDPKVAVTTAREITEFE 257

  Fly   160 -PLTREMFDKLWASLPKIPFPFKEYYW--------------REL---SELEEKIMSYGSEDDGFD 206
             .:...|.|:....:.|:..|....|.              |||   ..|.:.:..|..:.|
  Fly   258 QKIAAIMVDRRVGVMSKLYTPSDADYVDVSKLTQFVETVLDRELLANESLYQHVPDYLMKID--- 319

  Fly   207 SGDLVTRIPPFWMMPWPNGNITYENLSQMAHWLDIKANEFILTYIYMRLKLVAEGVSTESWHIDR 271
              :|||..||..:     .|..:              ||.:..:.|.|.:.|.|
  Fly   320 --ELVTETPPHVL-----ANYVF--------------NELLKHFYYERAESVVE----------- 352

  Fly   272 DQCAEQSR----QILSHPAAWLVEKNHPRLKEEPVLQDIFA---ELKQRFGQKLLANRNNFTRST 329
             ||..:.|    ::|.|   .|.|    :.::|..|:||:.   :|::.|       |.....|:
  Fly   353 -QCVSRVRDLFGELLDH---MLFE----QYEDEGTLKDIYVVWQQLQRSF-------RGVLQNSS 402

  Fly   330 QHFLLGKLKRM---RLRLSILPRNSSAQSMVRRIERHYRDVHMNASDYFGNLHIGLNHSRSHKKY 391
            .::|:.:.:..   :|..:.|..|..|:.   ...:.|.::|:...||..||...|||.....|.
  Fly   403 ANWLVPETREQLLEQLNTTSLVINGYAEV---NFTQRYEELHLKPRDYLHNLRTILNHQSLRVKV 464

  Fly   392 AQLWAIVFGRQLIPSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVPLSLLEPPF-YTHGQPSI 455
            .                              |..|..|......:::|::||:|.| ::...|..
  Fly   465 K------------------------------TQTSVTYDPVGKRVLLPVALLQPNFLWSRYYPKA 499

  Fly   456 LTYSALGFILGHELSHGFDS----EGMTFSSHGVGSSAVDRELDRNPRFQQELGCLRRRFGRKRY 516
            :.|.:||.:|..:|:|..:.    :..:|:                 .:.:...|.:.::||.|.
  Fly   500 VRYGSLGTLLAQQLAHSLEDASKWDAKSFA-----------------EYSKRKSCFKEQYGRLRL 547

  Fly   517 ------------EKFADASGLELAYSAYFD-TAQTDHK--RNRSAEEL-VTQKQQFFHNFAQFFC 565
                        |..||...:::||.||.. .|:.|..  .:.|..:| :..::.||.:|||.:|
  Fly   548 NGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQLNLGSRRLFFLSFAQLWC 612

  Fly   566 SDKELLQAHDHGSDRK----------RVNDAVAHFEPFREAFSCGPSPRR---RQCRLY 611
            :|     |::...|::          ||..|:::|..|...|:||.:.|.   ::|:|:
  Fly   613 ND-----ANEQFRDKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	142/685 (21%)
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	145/695 (21%)
		M13	73..664	CDD:189000	144/696 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454904
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940