Protein Alignment frma and Nepl12

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Alignment Length: 735
• Identity: 164/735 - (22%)
• Similarity: 266/735 - (36%)
• Gaps: 234/735 - (31%)

  Fly    19 VKSH--PQADPCQNFYKVACGNW-----------SASHATD-SY------ESFMDRLDYNYQEKL 63
            :||:  ...:||:|||:.||||:           |.|:..| :|      |..:.|:|      |
  Fly    60 MKSYMNQSVEPCENFYEYACGNYRNVKPDRYSPGSRSNLGDVTYTLIDITEQLLGRMD------L 118

  Fly    64 ADLLDNEREDDEPHFLQQLRNFYTAC----RKPLSQDQVLRILEHLIVMENIQNEELSVGLTAAF 124
            |:.|:...|      |...:.||.||    ..|.:....    .:|.::.:|.      |..|.
  Fly   119 AEALNVSSE------LAVAQRFYNACLGANLHPFNAADP----AYLSLIRSIG------GFPAV- 166

  Fly   125 RLQVLIDLNDSNTYDI----WKQLMSHRKHWDPNTTNREPLTREMFDKLWASLPKIPFPFKEYYW 185
                     |.:.:..    |..:.:|..::..|...||.|             ::.:||:.|
  Fly   167 ---------DGDAWKASNFNWINMSAHLANYGANGLIRETL-------------QLRYPFEPY-- 207

  Fly   186 RELSEL-----------------------EEKIMSY----GSEDDGFDSGDLVTRIPPFWM---- 219
            .:|.||                       ||::..|    |..:|..  .:.:..:..||.
  Fly   208 TKLPELGFDHIIVHEENISRNTTRAFRLNEERMHGYLRAFGLPEDRI--REAIAGVFAFWRDALE 270

  Fly   220 MP--------------WPNGNITYENLSQMAHWLDI-KANEFILTYIYMRLKLVAEGVSTESWHI 269
            :|              :|.... |.|:|    |..: ..|:....:.|:.|..|
  Fly   271 IPPQCEVFDPYRIKRVFPQSEY-YYNIS----WSGLHSTNKLFCDFYYVELDKV----------- 319

  Fly   270 DRDQCAEQSRQILSHPAAWLVEKNHPRLKEEPVLQDIFAELKQRFGQKLLANR----NNFTRSTQ 330
                ||...:.:.::.|..|:.:..|:|| .|..|..:..:......:.|.|:    |||:.:.:
  Fly   320 ----CARHRKAVANYLAMKLLYRFDPKLK-APRYQRNYCSVTLYQSMRFLFNKLYMANNFSEAKR 379

  Fly   331 HFLLGKLKRMRLRL-----------------------SILPRNSSAQ--SMVRRIERHYRDVHMN 370
            ..:...::.:|..|                       .|.||..|.|  ::..||.|....:.:
  Fly   380 LEMSEMVRELRKSLRKALEDADWLDAESRARALLKESRIQPRIGSFQDDALSDRIIREINSLKV- 443

  Fly   371 ASDYFGNLHIGLNH-----SR-SHKKYAQLWAIVFGRQLIPSRISKSDLYPTQVRGYGTYASAFY 429
            ..|.:...:|.|.|     :| |.:.:.:|               .:|..|.::. .|....|.|
  Fly   444 IEDRYAETNINLQHLVVQINRFSSRHFQEL---------------TNDTKPQKIL-TGLQVGAGY 492

  Fly   430 IVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSSHG--------VG 486
            ....|.:.|...::|||.|....|..|.:..||||:||||.||||:....|..:|        :.
  Fly   493 YTPDNSINVMAGVVEPPIYQRHLPISLKFGTLGFIVGHELIHGFDTTSSYFDGNGHMESLLSEIS 557

  Fly   487 SSAVDRELDRNPRFQQELGC-----LRRRFGRKRY--EKFADASGLELAYSAYFDTAQ--TDHK- 541
            ..|::   ||...:....|.     :.||...|..  |..||.|||..|.:||....|  .:|.
  Fly   558 QQALE---DRAECYMDYYGKYQVPEISRRVNGKTTLDENIADNSGLRQALTAYRSHRQQLLEHPG 619

  Fly   542 RNRSAEEL----VTQKQQFFHNFAQFFCSDKELLQAH-------DHGSDRKRVNDAVAHFEPFRE 595
            :.|.::.:    :|.:|.||..|||.|||..|  :.|       .|..|:.||...:::.|.|..
  Fly   620 QERISDAMPGLDLTPEQLFFLGFAQLFCSHYE--EEHYWKGLSDVHTFDQFRVLGVLSNSEDFFH 682

  Fly   596 AFSC----GPSPRRRQCRLY 611
            |::|    |..|..:.|||:
  Fly   683 AYNCSVGSGMRPGAKTCRLW 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	157/715 (22%)
Nepl12	NP_649924.1	M13	68..700	CDD:189000	159/723 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454910
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940