Protein Alignment frma and Nepl11

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 705
• Identity: 149/705 - (21%)
• Similarity: 227/705 - (32%)
• Gaps: 239/705 - (33%)

  Fly     7 LLELIVGLLVVQVKSHPQAD----PCQNFYKVACGNWSASHATDSYESFMDRLDYNYQE-KLADL 66
            ||.:...||.......|..|    |||:||...|     ||:.:..|:...|.....:| .:|.|
  Fly    21 LLRVETELLSFSHNLEPYLDTSKQPCQDFYGYVC-----SHSANLSETGRQRFQSLLKETDVAQL 80

  Fly    67 LDNEREDDEPHFLQQLRNFYTACR-----KPLSQDQVLR------ILEHLIVMENIQNEEL---- 116
            :|.|         .||.||:.:|.     :.|...|:.|      .||...|..:.:..:.
  Fly    81 MDME---------LQLINFFKSCESGRGVEALKGSQLYRQSGGWPSLEPNKVNASQRTNQTQRWL 136

  Fly   117 -------SVGLTAAFRLQVLIDLNDSNTYDIWKQLMSHRKHWDPNTTNREPLTREMFDKLWASLP 174
                   .||....|...|.:..|        |:|:.    ..|:.|.|..|.:
  Fly   137 GLLGYFHEVGAPYFFETSVTMQSN--------KRLVV----LQPDGTRRNTLRK----------- 178

  Fly   175 KIPFPFKEYYWRELSELEEKIMSYGSEDDGFDSGDLVTRIPPFWMMPWPNGNIT-YENLSQMAHW 238
                 |::       .:.|.:.|:|.|..                    ..::| .|.||.....
  Fly   179 -----FEQ-------RVGEVLQSFGIEQS--------------------RAHVTALEVLSLERSR 211

  Fly   239 LDI-KAN--EFILTYIYMRLKLVAEGVSTESWHIDRDQCAEQSRQIL--SHPAA--WLVEKNHPR 296
            .|| ||:  |..:.:.|...|.:..| :.....:|.|   ...|::|  ..|.|  .:|.|..||
  Fly   212 RDIVKADHVEDQVQFSYGNFKRIVFG-NASLIRLDWD---GYFRKLLGGKTPQASDTIVVKQLPR 272

  Fly   297 LKE----------------------------------EPVLQDIFAELKQRFGQKLLANRNNFTR 327
            |.|                                  |....|::|.:.||    :.|||....:
  Fly   273 LVEYFALLQNTSMVRLLNWIWTDYLMDIVDADCHQLSETYAGDLYAHVVQR----VTANRVELAQ 333

  Fly   328 STQHFLLGKLKRMRLRLSI----LPRNSSAQSMVRRIERHYRDVHMNASDYFGN-LHIGLNHSRS 387
              .:..|||....:|..|:    :.|.||.|                   :.|| :|..||  ..
  Fly   334 --MYSELGKAYTDQLGGSVWIDEISRQSSRQ-------------------FLGNIMHTTLN--GD 375

  Fly   388 HKKYAQLWAIVFGRQLIPSRISKSDLY----------PTQVRGYG-TYASAFYIVKQNMLIVPLS 441
            .:..|...:|:.||:.:...:.|...:          ..|||.|. .:|.....:.|:.|..||:
  Fly   376 ERLDAAYHSILLGRRSLYRNLEKLRKFQRTRRLASHSAQQVRRYAQMFAPVNAFLGQHNLSTPLN 440

  Fly   442 LLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSSHGVGSSAVDRELDRNPRFQQELG- 505
            .|                    :||...|....:.|.:..:.|...|: |.| .|...|||.:|
  Fly   441 YL--------------------LLGEFFSRSLVAAGSSSRTQGAWRSS-DSE-RRFAIFQQCVGK 483

  Fly   506 ----------CLRRRFGRKRYEKF-ADASGLELAYSAYFDTAQTDHKRNRSAEELVTQKQQFFHN 559
                      .|.:|.....|.:: |..:||         ..:.|......:.::..|:..|..:
  Fly   484 QTNAIDLLLSLLAQRQALSAYGQWLATQAGL---------VERVDAVLAAGSSKMSLQRLFFVTS 539

  Fly   560 FAQFFCSDKELLQAHDHGSDRKR-VNDAVAHFEP-FREAFSCGPS----PRRRQC 608
            ......|:...||     .|||| |..|.....| |.|||.|.|.    |:.::|
  Fly   540 LLVDCRSELGALQ-----QDRKRQVTHATLRNSPEFLEAFRCRPGDVLYPQDQRC 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	141/674 (21%)
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	142/679 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010