Protein Alignment frma and phex

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001307259.1
• Gene: phex / 386969
• ZFINID: ZDB-GENE-030103-2
• Length: 745
• Species: Danio rerio
• Alignment Length: 712
• Identity: 154/712 - (21%)
• Similarity: 271/712 - (38%)
• Gaps: 181/712 - (25%)

  Fly    20 KSHPQADPCQNFYKVACGNWSASHA----TDSYESFMDRLDYNYQEKLADLLDNEREDDEPHFLQ 80
            |.....|||.:||:.|||.|...:.    :.|| .....|..|...||.:||:......:...::
Zfish    67 KMDQSVDPCDDFYQYACGGWLRENPIPEDSSSY-GIYPWLRQNVDLKLKELLEQPVRSGDIEAVK 130

  Fly    81 QLRNFYTACRKPLSQDQVLRILEHLIVMENIQNEEL-------SVGLTAAF-------------- 124
            :.:..|.:|    ..:..|.|.:...:::|::.:|.       ::|.::.:
Zfish   131 KAKVLYASC----MNESALEIEDANPLLKNLKQKEFRWPVLGDALGSSSRWVESQFNLLETLAQI 191

  Fly   125 ----------RLQVLIDLNDSNTY----DIWKQLMSHRKHWDPNTTN----REPLTREMFD---K 168
                      ||.|..|..:||.|    |.....:|.|:.:..|||.    ||.|.|.|.|   .
Zfish   192 RSQHSKSVLIRLFVAPDDKNSNQYIIKLDQASLSLSSREDYITNTTEAQMYREALLRLMVDVSVM 256

  Fly   169 LWAS-----------------LPKIPFPFKE------YYWRELSELEEKIMSYGSEDDGF----- 205
            |.||                 |.:|..|::.      |....||:|:..:..:...  ||
Zfish   257 LGASEQAAEAQMKSVLDFEMKLAQIVIPYENRTSENMYNKYSLSKLQRTVPDFNWL--GFVRAVI 319

  Fly   206 -----------DSGDLVTRIPPFWMMPWPNGNITYENLSQMAHWLDIK--ANEFI---------- 247
                       .|..::.|.|.:           :::|.::.:..|.:  ||..|
Zfish   320 DTELYPDLKISSSEQVIVRAPQY-----------FKDLFKLINATDTRTVANYVIWRSVFSRITT 373

  Fly   248 ----LTYIYMRLKLVAEGVS--TESWHIDRDQCAEQSRQILSHPAAWLVEKNHPRLKEEPVLQDI 306
                ..|.|:....|..|.:  |..|    |:|.......|.:.|..|....|.:..::.:::::
Zfish   374 LSRRFLYRYLDFARVTTGTTSLTPRW----DKCVNYVENTLIYAAGRLFVDKHFQEDKKHMMEEL 434

  Fly   307 FAELKQRFGQKLLANRNNFTRSTQHFLLGKLKRMRLRLSILPRNSSAQSMVR--RIERHYRDVHM 369
            ...::..|...|..........|:...:.|..      ::||:......::.  .|....:.:..
Zfish   435 INGIRWAFIDILEKENEWMDEETKRKAIDKAH------AVLPKVGYPDFILNDTYINEDIKRLAF 493

  Fly   370 NASDYFGNLHIGLNHSRSHKKYAQLWAIVFGRQLIPSRISKSDLY--PTQVRGYGTYASAFYIVK 432
            ..:|||||:...|       |:.....|.:.|:.:|    :::.:  ||.|       :|||...
Zfish   494 TMTDYFGNVMQTL-------KFIAQSDIGWLRKTVP----RTEWFTNPTTV-------NAFYSSS 540

  Fly   433 QNMLIVPLSLLEPPFYTH-GQPSILTYSALGFILGHELSHGFDSEGMTFSSHG-----VGSSAVD 491
            .|.:..|...|:.||:.. ..|..|:|.|:|.|:||||:||||:.|..:...|     ..:|:::
Zfish   541 TNQIRFPAGELQKPFFWGLNYPRSLSYGAIGVIVGHELTHGFDNNGRKYDKDGNLDQWWSNSSIN 605

  Fly   492 RELDR--------NPRFQQELGCLRRRFGRKRYEKFADASGLELAYSAYFDTAQTDHKRNRSAEE 548
            |..::        |..:.:|.| |..:..|...|..||..|:..::.||  ....:.:|....|.
Zfish   606 RFTEKTQCMIDQYNSYYWKEAG-LNVKGKRTLAENIADNGGIRESFRAY--RRWVEKERGGVEEP 667

  Fly   549 L-----VTQKQQFFHNFAQFFC------SDKELLQAHDHGSDRKRVNDAVAHFEPFREAFSC 599
            |     :|..|.||.::|...|      :.::.:|:..|...:.||..|:::||.||:||:|
Zfish   668 LLPGVGLTHNQLFFLSYAHVRCNAYRPEAARDQIQSGAHSPPKYRVIGAMSNFEEFRKAFNC 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	153/707 (22%)
phex	NP_001307259.1	PepO	61..744	CDD:226118	154/712 (22%)
		M13	72..743	CDD:189000	153/707 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010