Protein Alignment frma and Nepl9

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 738
• Identity: 142/738 - (19%)
• Similarity: 229/738 - (31%)
• Gaps: 292/738 - (39%)

  Fly     3 FKLRLLELIVGLLVVQVKSHPQADPCQNFYKVACGNWSASHATDSYESFMDRLDYNYQEKLADLL 67
            :|..|.:|      |::| :...|||.:||..||||:..:...:| :.|:....||.|:::
  Fly    46 YKSNLQQL------VKIK-NDSMDPCDDFYAHACGNFDQTKEENS-DDFLPPYLYNKQDRM---- 98

  Fly    68 DNEREDDEPHFLQQLRNF-----------YTACRKPLSQDQVLRILEHLIVMENIQNEELSV--- 118
                    ..|..::.||           ||.|||                     .||.:|
  Fly    99 --------NFFTAEVGNFETIPGRLISQLYTECRK---------------------REERNVFTP 134

  Fly   119 -GLTAAFRLQVLIDLNDSNTYDIWKQLMSHRKHWDPNTTNREPLTREMFDKLWASLPKIPF---- 178
             .||:                           ||:           .|.|       :|||
  Fly   135 TRLTS---------------------------HWE-----------RMLD-------EIPFLARH 154

  Fly   179 -------PFKEYYWRELSELEEKIMSYGSEDDGFDSGDLVTRIPPFWMMPWPNGNITYENLSQMA 236
                   ||.::.|       |:...||..:               |::  .:..:....|..:.
  Fly   155 KEVLSSWPFLKHQW-------ERRRLYGQLN---------------WIV--LSAQLAAHGLPTLL 195

  Fly   237 HWLDIKANEFILTYIYM----------------RLKLVAEG----VSTESWHIDRDQCAEQSRQI 281
            |..      |.|..||:                .|..|.||    ||....|..|..|.|...::
  Fly   196 HIY------FALDTIYVSPMEELPCPSIADFQSSLSDVLEGRHHQVSRIISHEMRVLCREMRGEL 254

  Fly   282 -LSHPAAWLVEKNHPRLKEEPVL---------QDIFAELKQRFGQKLLANRNNF----------- 325
             |....:.....|..|..||.:|         |..||.|  .|.::.|.....|
  Fly   255 PLVRSLSQNTRTNTSRPGEEQLLLDENTMDYFQQYFAAL--NFSEERLVGARKFPLDVEKITQAW 317

  Fly   326 -------TRSTQHFLLGKLKRMRLRLSILPRNSSAQSMVRRIE--------RHY-RDVHMNASDY 374
                   ||...::::.: .|.:||.....|.|.....:...|        ||. |:|.:.:...
  Fly   318 EVLRHTETRIVYNYVMWQ-AREQLRYPDCYRVSEEFERLLHAEYWQWHVLRRHLSREVALASYQL 381

  Fly   375 FGNLHIGLNHSRSHKK--YAQLWAIVFGRQLIPSRISKSDLYPTQV------------------R 419
            .......|..|:..::  |..||         |:.:.|.:|...::                  .
  Fly   382 HTTRFQKLRRSKLSRRDWYGHLW---------PASVEKKELQVARILQNHAENYLNITELNENYE 437

  Fly   420 GYGTYASAFYIVKQNMLIVPLSLLEPPFYTH-------GQPSILTYSALGFIL--GHELSHGFDS 475
            |.....::||   .|:||:..:.|...|.:.       .||:......|.|:|  .|..::.:
  Fly   438 GLKLEKNSFY---ANLLILRRAQLRHSFVSPYVDEEDVNQPAYFLRHFLHFVLLSLHRPTYHY-- 497

  Fly   476 EGMTFSSHGVGSSAVDRELDRNPRFQQE-------LGCLRRR----FGRKRYEKFADASGLELA- 528
                :::||:       ||.|..|...:       :.||.|:    :..|....:......|:|
  Fly   498 ----YATHGL-------ELWRESRLLLDTDGHYTAMDCLERQSFQHYDAKLAPIYRPLGSHEIAE 551

  Fly   529 -YSAY--FDTAQTDH------KRNRSAEELV------TQKQQFFHNFAQFFCS-DKELLQAHDHG 577
             :..|  |..:.||:      :|...||..|      ...:..|:..||..|: ..|:..|
  Fly   552 IFQFYRSFQYSLTDYHFWLQGERFAFAETFVLDYFGLNPHRVLFYAVAQQLCNRQTEIFAA---- 612

  Fly   578 SDRKRVNDAVAHFEPFREAFSCG 600
                ::|....:...|:|||.||
  Fly   613 ----QLNRGYMNLPEFQEAFKCG 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	137/716 (19%)
Nepl9	NP_609815.1	GluZincin	62..>84	CDD:301352	10/22 (45%)
		GluZincin	<579..642	CDD:301352	15/61 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454850
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030