Protein Alignment frma and Nepl6

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 703
• Identity: 165/703 - (23%)
• Similarity: 279/703 - (39%)
• Gaps: 151/703 - (21%)

  Fly    10 LIVGLLVVQVKSHP-----QADP------------------CQNFYKVACGNWSASHATDSYESF 51
            ||..|.:|.:.:.|     :|||                  |..:::.|||.::..|..|.:...
  Fly     3 LIACLFIVPICAAPTTQNVEADPNSRLMNNILSYVAEDSSACGTYFQYACGKYAVRHRDDPFTEI 67

  Fly    52 MDRLDYNYQEKLADLL-DNEREDDEPHFLQ-----QLRNFYTACRK------------------- 91
            :..||:.....|..|: :..:....|.|.:     ::.:||..||:
  Fly    68 IQMLDHKVNGNLVQLMHELHQRSQSPGFNESSVEAKVLHFYRTCREAPPSTRKMEHYLRLAPPGQ 132

  Fly    92 --------------PLSQDQVLRILEHLIVMENIQNEELSVGLTAAFRLQVLIDLNDSNTYDIWK 142
                          |.:|.:.::.|.||          ...|.|... :.||:..:..|
  Fly   133 ALTWPQFMPRGEPWPKAQFKWMKSLGHL----------YRYGFTNVL-VNVLVLRSSEN------ 180

  Fly   143 QLMSHRKHWDPNTTNREPLTREM--FDKLWASLPKIPFPFKEY--YWRELSELEE--KIMSYGSE 201
               |:|...|.:..:.|...:.:  |....|:|..|..|.|..  ..|::..||.  ::::...:
  Fly   181 ---SNRFRLDISMPSLEGDAQHLGGFLSTLATLQIIGVPTKSILPLVRKIRRLESAIRVLTEVDD 242

  Fly   202 DD-------------------GFDSGDLVTRIPPFWMMPWPNGNITYENLSQMAHWLDIKANEFI 247
            ||                   ||....:...:...::|...|... :..|.::   :|....|.:
  Fly   243 DDESETWTLRQWEYKTGYAWQGFVESIVGHSVSHHYVMQAQNAKY-FTGLKRL---MDSTDAEVV 303

  Fly   248 LTYIYMR--LKLVAEGVSTESWHIDRDQCAEQSRQILSHPAAWLVEKNHPRLKEEPVLQD----- 305
            ..||..|  |.|:.:.:.:.. |||   |....|:.::..:..|.::   |..:...||.
  Fly   304 ANYIMTRFVLYLIDDFIDSNE-HID---CVTDMRRNMNLASNLLYKE---RFLDPATLQQYTQEV 361

  Fly   306 --IFAELKQRFGQKLLANRNNFTRSTQHFLLGKLKRMRLRLSILPRNSSAQSMVRRIERHYRDVH 368
              :|.:|:::|..::..||...|......:..|.:.:.|.:..|||....:|.|   .|||.|:.
  Fly   362 TKVFEQLRRQFLLQINENRLGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSFV---SRHYEDLV 423

  Fly   369 MNASDY-FGNLHIGLNHSRSHKKYAQLWAIVFGRQLIPSR---ISKSDLYPTQVRGYGTYASAFY 429
            ....|: :...|:.|...|:.|:..||      .|..|:.   ...||  |......|.|    |
  Fly   424 FPLPDFDYAREHLNLLEFRTRKQVLQL------NQSAPTPDEFFYLSD--PKTAMSSGPY----Y 476

  Fly   430 IVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSSHGVGSSAVDREL 494
            :::.|:::||..||:.||:......|..||.|||:|.|||.|..|:.|:.:..:| ....:..::
  Fly   477 LMRLNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLAHELMHSVDTVGLYYDRYG-NIHEIGPQI 540

  Fly   495 DRNPRFQQELGCLRRRFGRKRYEKFADASGLELAYSAYFDTAQTDHKRNRSAEELVTQKQQFFHN 559
            ..:|||...|.||.|...:...|:.||.:||:||||.||   |...:.:.:....:..:|.||.|
  Fly   541 SSSPRFVAGLQCLNRNSTQYLDERIADIAGLDLAYSTYF---QNSSQMSLTDFTTIPPQQIFFLN 602

  Fly   560 FAQFFCSDKELLQAHDHGSDRKRVNDAVAHFEPFREAFSC-GPSPRRRQCRLY 611
            .|||||.|.:.:....|.:|..|:...:..|.||.|||.| ..|.:..:|:|:
  Fly   603 LAQFFCGDGDPINFVGHDNDETRLQQMLNGFAPFHEAFGCPAKSNQPEKCQLW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	157/671 (23%)
Nepl6	NP_609023.3	M13	42..653	CDD:189000	155/660 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469643
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940