Protein Alignment frma and Nepl4

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 637
• Identity: 146/637 - (22%)
• Similarity: 256/637 - (40%)
• Gaps: 117/637 - (18%)

  Fly    24 QADPCQNFYKVACGNWSASHATDSYESFMDRLDYN--YQEKLADLLDNER--EDDEPHFLQQLRN 84
            :.:||::||..|||.|.|.|.:.:..:.:.....|  |::....||.|..  |...|.|.:.|.:
  Fly    57 EKNPCEDFYAYACGKWRAKHGSHTTATMISESQINRQYEDLFLQLLRNPSAPEYGYPMFAKVLAH 121

  Fly    85 FYTACRKPLSQDQVLRILEHLIVMENIQNEELSVGLTAAFRLQVLIDLNDSNTYDIWKQ------ 143
             |.:| ..|.:..:.|.:|.|       :.:|...|.:...:.:|..|.....:..:.|
  Fly   122 -YQSC-IALEKPDLRRYIELL-------DRDLLASLNSTHWMHLLAALGRYGYHGHYVQVEVRWY 177

  Fly   144 --------LMSHRKHWDPNTTNREPLTREMFDKL------WASLPKIPFPFKEYYWRELSELEEK 194
                    |:.|.:|.:.:      ||::::|.|      |..|.::...|:        .||:.
  Fly   178 NATHHMIFLLPHNRHLNLS------LTQDIYDALSQDGSSWPPLHQLQEQFR--------SLEQN 228

  Fly   195 IMSYG---SEDDGFDS---GDLVTRIPPFWMMPWPN-----------GNITY--------ENLSQ 234
            ::...   |.||.|.:   ..:.|.:|.   :.|..           ||..:        |.|.:
  Fly   229 LVRLAKPHSADDTFRNYSLDQIRTEVPG---LHWDEALRTQLGRSVPGNHVFQVDDLDAIEGLVE 290

  Fly   235 MAHWLD-IKANEFILT-YIYMRLKLVAEGVST-ESWHIDRDQ-CAEQSRQILSHPAAWLVEK--- 292
            ..:.:| :..|.:.|. ::...|:|....::| ||....|.: |....|:.:..|..::.|:
  Fly   291 YLNTVDTLLLNRYSLARFLSHLLELPHNPLATWESGQRSRGRNCIRHMRRSVYLPMNYVYERSFY 355

  Fly   293 NHPRLKEEPVLQDIFAELKQRFGQKLLANRNNFTRSTQHFLLGKLKRMRLRLSILPRNSSAQ--- 354
            :..|..:|.|:..:|.:|:.:...::..|..|.::.....|..|:.:||:.:..||.|.:.|
  Fly   356 SRRRHADELVIHSVFQQLQSQLELRVQHNAFNLSQDLVKSLQAKVHQMRINVGNLPPNVTEQFYW 420

  Fly   355 SMVRR--IERHYRDVHMNASDYFGNLHIGLNHSRSHKKYAQLWAIVFGRQLIPSRISKSDLYPTQ 417
            ...||  :.|.:.:.|:|:..|:..|...| .|.|.::...:|.         |....:..:|..
  Fly   421 DSDRRWSVGRDFYENHLNSLLYYYTLVADL-ESSSDQEERDIWY---------SFNMHTPEFPDN 475

  Fly   418 VRGYGTYASAFYIVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSS 482
            :.     |:.::....|::.||.|.::.||:.......|.|..|...||||:.|.||::.:.:.:
  Fly   476 ID-----ATPYFYCLGNIIFVPYSYVKRPFFDANFWPALLYGDLANTLGHEIMHAFDTDLVDYDA 535

  Fly   483 HGVGSSAVDRELDRNPRFQQELGCLRRRFGRKRYEKFADASGLELAYSAYFDTAQTDHKRNRSAE 547
            .|...:..| :|.....:...:|||... .....|:.:|.||..||...|.....|.....|
  Fly   536 QGNLRNFSD-QLGEVELYNGAVGCLNSS-AVMLNERTSDVSGSRLAMQTYGGDWLTRSGNGR--- 595

  Fly   548 ELVTQKQQFFHNFAQFFCSDKELLQAHDHGSDRKRVNDAVAHFEPFREAFSC 599
                   .:|..||.|||.| |..|.||.||  :|:|.|:.....|.|.|.|
  Fly   596 -------LYFLQFAHFFCGD-EGDQYHDSGS--QRLNYALGQVPQFAEVFRC 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	146/636 (23%)
Nepl4	NP_609019.1	PepO	51..643	CDD:226118	146/637 (23%)
		GluZincin	59..649	CDD:301352	146/635 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010