Protein Alignment frma and Nep6

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001245645.1
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 715
• Identity: 157/715 - (21%)
• Similarity: 251/715 - (35%)
• Gaps: 208/715 - (29%)

  Fly     8 LELIVGLLVVQVKS----HPQAD--------PCQNFYKVACGNW--SASHATDSYESFMDRLDYN 58
            |.:|:|::::::.:    ..|.|        ||:||::.|||||  :.|...........:...|
  Fly    11 LVVILGVMLLKLAAAQDCQQQLDNDTDAEVKPCENFHQYACGNWYSNTSQRILGAHDMRSKWVAN 75

  Fly    59 YQEKLADLLDNEREDDE-------PHFLQQLRNFYTACRKPLSQDQVLRILEHLIVMENIQNEEL 116
            .:.:|...|:.....|.       .....||...|..|   |...|.:|.....:.... .|..|
  Fly    76 LKLQLIRYLEESSSTDSFSANTSVTTSTAQLGTLYRCC---LLSGQSIRTYTDALSRSG-ANFPL 136

  Fly   117 SVGLTAAFRLQVLID--LNDSNTYDIWKQLMSHRKHWDPNTTNREPLTREMFDKLWASLPKIPFP 179
            ....|......||.:  |.......:|:.|:  :.:|.........:....||.|........|.
  Fly   137 LANHTGGSFDWVLANAALRTYGAQGLWRLLV--KDNWQSADQRIFYMLPPKFDLLGRDDELNEFL 199

  Fly   180 FKEYY----------WRELSELEEKIMSYGSE------DDGFDS---------GDLVTRIPPFWM 219
            ::.|.          .|..:.|.||::::...      :|...:         .||.:::|...:
  Fly   200 YQRYLKILLLELGLRVRRAALLAEKLVAFEKSLQKLLPNDAEQTLVLRKPQSLKDLESQLPRLEL 264

  Fly   220 MPWPNGNITYENLSQMAHWLDIKANEFI--LTYIYMRLKLVAEGVS----TESW----------- 267
            ..:      :|.:.:...| |.|....:  |.|:....:|:||..|    ..:|
  Fly   265 KRY------FETILEGIDW-DSKTLLLVADLDYLQGLQRLLAEHTSDPMVLSTWLLLQLPAYFEL 322

  Fly   268 --HID------RDQCAEQSRQILSHPAAWLVEKNHPRLKEEPVL----QDI-----------FAE 309
              |.|      |:.|.||.|:::.....        ||:.:.||    ||:           |.:
  Fly   323 RLHDDDKLGNQRNHCLEQLRKLMPGQLG--------RLQMQLVLGESYQDVYDTAIQQIAVLFRD 379

  Fly   310 LKQRFGQKLLANRN---NFTRSTQHFLLGKLKRMRLRLSILPRNSSAQSMVRRIERHYRDVHMNA 371
            |||:|  :|:.|..   |....|::....||:.|||   :.||....               :|.
  Fly   380 LKQQF--ELVLNETEVFNEDLVTRNLARDKLRAMRL---LTPRLQDP---------------ING 424

  Fly   372 SDYFGNLHIG---------LNHSRSHKKYAQLWAIVFGRQLIPSRISKSDLYPTQVRGYGTYASA 427
            ..  |...:|         |:.|::..:|.|    |||..:            |.|.......:|
  Fly   425 GP--GTPQLGGNCDANLLQLSLSQAKLEYRQ----VFGEPV------------TSVPADPLSVNA 471

  Fly   428 FYIVKQNMLIVPLSLLEPPFY---------THGQPSILTYSALGFILGHELSHGFDSEGMTFSSH 483
            :|.:|.|.:.:||.|:..|..         |..:.|    :.||:||.||:.|.||.:|:.:.:.
  Fly   472 YYRLKLNRIELPLGLMATPLIQQQCSKEADTRAKLS----AGLGYILAHEMVHAFDLDGLNYDAT 532

  Fly   484 GV------GSSAVDRELDRNPRFQQELGC-LRRRFGRKRY---EKFADASGLELAYSAYFDTAQT 538
            |.      .:.|:       .||....|| |..|:.....   |..||..||.||...|
  Fly   533 GQLANGQWSARAI-------IRFGLRAGCYLGVRYSNATLTVNENIADTEGLRLALDTY------ 584

  Fly   539 DHKRNRSAEELVTQKQQFFHNFAQFFC----SDKELLQAHDHGSDRKRVNDAVAHFEPFREAFSC 599
               |:||.   .|..:.||..|||.:|    |...|.|   |....:|||:.|.:...|.:.|.|
  Fly   585 ---RHRSG---ATNLRTFFVAFAQNWCGTVASTSGLSQ---HAGHAERVNNVVGNMPEFGDTFEC 640

  Fly   600  599
              Fly   641  640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	153/694 (22%)
Nep6	NP_001245645.1	PepO	35..655	CDD:226118	152/691 (22%)
		M13	40..653	CDD:189000	152/686 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469658
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940